Research > Nutrition, Metabolism and Cellular Stress

Metabolic physiopathology

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The general research objective of our group is to study the role of metabolism and oxidative stress (including free radical chemistry, redox biology and antioxidants) in the aging process and age-associated pathologies. Thus, we investigate the role of metabolism and oxidative stress in animal (vertebrates and invertebrates) and human models in which the rate of aging and longevity are different, or have been experimentally modified (e.g., caloric restriction, methionine restriction, and genetic manipulations) or pathologically affected (e.g., neurodegenerative and metabolic diseases).

According to this goal, our main research areas are the following:

1. To delve into the role of metabolism and oxidative stress in the biological process of aging and the traits that define longevity.
2. To unravel the role of metabolism and oxidative stress in the origin and development of age-related pathologies, with special emphasis on neurodegenerative diseases.
3. To apply the functional properties of food to human health.