Groups
Publications
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Torres, P; Rico-Rios, S; Ceron-Codorniu, M; Santacreu-Vilaseca, M; Seoane-Miraz, D; Jad, Y; Ayala, V; Mariño, G; Beltran, M; Miralles, MP; Andrés-Benito, P; Fernandez-Irigoyen, J; Santamaria, E; López-Otín, C; Soler, RM; Povedano, M; Ferrer, I; Pamplona, R; Wood, MJA; Varela, MA; Portero-Otin, M
TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition
ACTA NEUROPATHOLOGICA 148 45-45. .
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Ceron-Codorniu, M; Torres, P; Fernández-Bernal, A; Rico-Rios, S; Serrano, JCE; Miralles, MP; Beltran, M; Garcera, A; Soler, RM; Pamplona, R; Portero-Otín, M
TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells
Redox Biology 75 103301-103301. .
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Gil-Sánchez A.; Gonzalo H.; Canudes M.; Nogueras L.; González-Mingot C.; Valcheva P.; Torres P.; Serrano J.C.; Peralta S.; Solana M.J.; Brieva L.
Can Glatiramer Acetate Prevent Cognitive Impairment by Modulating Oxidative Stress in Patients with Multiple Sclerosis?
PHARMACEUTICALS 17 -. .
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Sancho--Saldaña, A; Gil-Sánchez, A; González-Mingot, C; Peralta, S; Solana, MJ; Torres, P; Juanes, A; Quibus, L; Ruiz, E; Sanpedro, E; Quirant-Sánchez, B; Martínez-Cáceres, E; Tello, CR; Presas-Rodríguez, S; Rubio, SG; Baron, BP; Ramio-Torrenta, L; Sotoca, J; González-Suarez, I; Eichau, S; Prieto-Gonzalez, JM; Quilez, MRB; Sabin-Muñoz, J; Sánchez-López, AJ; Calatayud, GL; Calles, C; Sempere, AP; Garces, M; Carmona, O; Moral, E; Hervas, JV; Blanco, Y; Sola-Valls, N; Lara, NT; Forero, L; Brieva, L
Seroprevalence of SARS-CoV-2 in Patients with Multiple Sclerosis under Disease-Modifying Therapies: A Multi-Centre Study
Journal of Clinical Medicine 12 -. .
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Torres P; Pamplona R; Portero-Otin M
Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes.
Neural Regeneration Research 18 1725-1726. .
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Brewer, MK; Torres, P; Ayala, V; Portero-Otin, M; Pamplona, R; Andres-Benito, P; Ferrer, I; Guinovart, JJ; Duran, J
Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis
JOURNAL OF NEUROCHEMISTRY 168 744-759. .
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Torres P; Sancho-Saldaña A; Gil Sánchez A; Peralta S; Solana MJ; Bakkioui S; González-Mingot C; Quibus L; Ruiz-Fernández E; San Pedro-Murillo E; Brieva L
A prospective study of cellular immune response to booster COVID-19 vaccination in multiple sclerosis patients treated with a broad spectrum of disease-modifying therapies.
JOURNAL OF NEUROLOGY 270 1-12. .
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Muñoz-Basagoiti J; Monteiro FLL; Krumpe LRH; Armario-Najera V; Shenoy SR; Perez-Zsolt D; Westgarth HJ; Villorbina G; Bomfim LM; Raïch-Regué D; Nogueras L; Henrich CJ; Gallemí M; Moreira FRR; Torres P; Wilson J; D'arc M; Marfil S; Herlinger AL; Pradenas E; Higa LM; Portero-Otin M; Trinité B; Twyman RM; Capell T; Tanuri A; Blanco J; Izquierdo-Useros N; Rech EL; Christou P; O'Keefe BR
Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 -. .
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Torres, P; Anerillas, C; Ramirez-Nunez, O; Fernàndez A; Encinas, M; Povedano, M; Andres-Benito, P; Ferrer, I; Ayala, V; Pamplona, R; Portero-Otin, M
The motor neuron disease mouse model hSOD1-G93A shows a non-canonical profile of senescence biomarkers.
DISEASE MODELS & MECHANISMS 15 -. .
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Sancho-Saldana, A; Gil Sánchez A; Quirant-Sanchez, B; Nogueras, L; Peralta, S; Solana, MJ; Gonzalez-Mingot, C; Gallego, Y; Quibus, L; Ramo-Tello, C; Presas-Rodriguez, S; Martinez-Caceres, E; Torres, P; Hervas, JV; Valls, J; Brieva, L
Seroprevalence of SARS-CoV-2 in a Cohort of Patients with Multiple Sclerosis under Disease-Modifying Therapies.
Journal of Clinical Medicine 11 -. .
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Jové M; Cabré R; Mota-Martorell N; Martin-Garí M; Obis È; Ramos P; Canales I; Galo-Licona JD; Sol J; Nogueras L; Torres P; Portero-Otín M; Ayala V; Ferrer I; Pamplona R
Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 -. .
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Rossi C; Fernàndez A; Torres P; Ramirez-Nuñez O; Granado-Serrano AB; Fontdevila L; Povedano M; Pamplona R; Ferrer I; Portero-Otin M
Cell Stress Induces Mislocalization of Transcription Factors with Mitochondrial Enrichment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 -. .
Projects
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Convocatòria d’Ajuts 2019 de Promoció de la Recerca en Salut – 7a Edició
- Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.