Groups
Publications
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Torres-Querol C; Torres P; Vidal N; Portero-Otín M; Arque G; Purroy F
Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype.
SCIENTIFIC REPORTS 11 15752-15752. .
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Ramírez-Nuñez O; Jové M; Torres P; Sol J; Fontdevila L; Romero-Guevara R; Andrés-Benito P; Ayala V; Rossi C; Boada J; Povedano M; Ferrer I; Pamplona R; Portero-Otin M
Nuclear lipidome is altered in amyotrophic lateral sclerosis: A pilot study.
JOURNAL OF NEUROCHEMISTRY 158 482-499. .
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Sol J; Jové M; Povedano M; Sproviero W; Domínguez R; Piñol-Ripoll G; Romero-Guevara R; Hye A; Al-Chalabi A; Torres P; Andres-Benito P; Area-Gómez E; Pamplona R; Ferrer I; Ayala V; Portero-Otín M
Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression.
Brain Communications 3 -. .
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Jové M; Mota-Martorell N; Torres P; Portero-Otin M; Ferrer I; Pamplona R
New insights into human prefrontal cortex aging with a lipidomics approach.
EXPERT REVIEW OF PROTEOMICS 18 1-12. .
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Jové M; Mota-Martorell N; Torres P; Ayala V; Portero-Otin M; Ferrer I; Pamplona R
The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology.
Life-Basel 11 -. .
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Torres, P; Andres-Benito, P; Fernàndez-Bernal A; Ricart, M; Ayala, V; Pamplona, R; Ferrer, I; Portero-Otin, M
Selected cryptic exons accumulate in hippocampal cell nuclei in Alzheimer's disease with and without associated TDP-43 proteinopathy.
BRAIN 143 20-. .
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Torres, P; Cacabelos, D; Pairada, J; Bauer, KC; Boada, J; Fontdevila, L; Rossi, C; Povedano, M; Ferrer, I; Pamplona, R; Finlay, BB; Portero-Otin, M; Ayala, V
Gender-Specific Beneficial Effects of Docosahexaenoic Acid Dietary Supplementation in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice.
NEUROTHERAPEUTICS 17 269-281. .
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Torres, P; Ramirez-Nunez, O; Romero-Guevara, R; Bares, G; Granado-Serrano, AB; Ayala, V; Boada, J; Fontdevila, L; Povedano, M; Sanchis, D; Pamplona, R; Ferrer, I; Portero-Otin, M
Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue
Autophagy 14 1398-1403. .
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Cacabelos, D; Ayala, V; Granado-Serrano, AB; Jove, M; Torres, P; Boada, J; Cabre, R; Ramirez-Nunez, O; Gonzalo, H; Soler-Cantero, A; Serrano, JCE; Bellmunt, MJ; Romero, MP; Motilva, MJ; Nonaka, T; Hasegawa, M; Ferrer, I; Pamplona, R; Portero-Otin, M
Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis
NEUROBIOLOGY OF DISEASE 88 148-160. .
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Cacabelos, D; Ramirez-Nunez, O; Granado-Serrano, AB; Torres, P; Ayala, V; Moiseeva, V; Povedano, M; Ferrer, I; Pamplona, R; Portero-Otin, M; Boada, J
Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS
Acta neuropathologica communications 4 3-3. .
Projects
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Convocatòria d’Ajuts 2019 de Promoció de la Recerca en Salut – 7a Edició
- Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
