Manuel Portero Otin
Degree: PhD
973 702 408
manuel.portero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/B-7122-2009
Groups
Publications
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Sanz, Alberto; Soikkeli, Mikko; Portero-Otin, Manuel; Wilson, Angela; Kemppainen, Esko; McIlroy, George; Ellila, Simo; Kemppainen, Kia K.; Tuomela, Tea; Lakanmaa, Matti; Kiviranta, Essi; Stefanatos, Rhoda; Dufour, Eric; Hutz, Bettina; Naudi, Alba; Jove, Mariona; Zeb, Akbar; Vartiainen, Suvi; Matsuno-Yagi, Akemi; Yagi, Takao; Rustin, Pierre; Pamplona, Reinald; Jacobs, Howard T.
Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 9105-9110. .
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Fourcade, Stephane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudi, Alba; Portero-Otin, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona, Reinald; Aubourg, Patrick; Pujol, Aurora
Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.
HUMAN MOLECULAR GENETICS 19 2005-2014. .
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Ilieva, Ekaterina V.; Naudi, Alba; Kichev, Anton; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel
Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease.
FREE RADICAL BIOLOGY AND MEDICINE 48 1302-1310. .
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Naudí A; Jové M; Ayala V; Portero-Otín M; Pamplona R
Glicación de proteínas mitocondriales, estrés oxidativo y envejecimiento.
Revista espanola de geriatria y gerontologia 45 156-166. .
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Martinez, Anna; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidre
Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.
BRAIN PATHOLOGY 20 281-297. .
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Muntane, Gerard; Janue, Anna; Fernandez, Nuria; Odena, Maria Antonia; Oliveira, Eliandre; Boluda, Susana; Portero-Otin, Manuel; Naudi, Alba; Boada, Jordi; Pamplona, Reinald; Ferrer, Isidre
Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids.
NEUROCHEMISTRY INTERNATIONAL 56 318-328. .
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Terni, Beatrice; Boada, Jordi; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidro
Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.
BRAIN PATHOLOGY 20 222-233. .
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Fernandez, Liana Lisboa; Carmona, Marga; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Schroeder, Nadja; Ferrer, Isidro
Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice.
Journal Of Alzheimers Disease 19 1069-1080. .
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Quiles, Jose L.; Pamplona, Reinald; Carmen Ramirez-Tortosa, M.; Naudi, Alba; Portero-Otin, Manuel; Araujo-Nepomuceno, Eduardo; Lopez-Frias, Magdalena; Battino, Maurizio; Ochoa, Julio J.
Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart.
MECHANISMS OF AGEING AND DEVELOPMENT 131 38-47. .
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Kichev, Anton; Ilieva, Ekaterina V.; Pinol-Ripoll, Gerard; Podlesniy, Petar; Ferrer, Isidro; Portero-Otin, Manuel; Pamplona, Reinald; Espinet, Carme
Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.
AMERICAN JOURNAL OF PATHOLOGY 175 2574-2585. .
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Negre-Salvayre, Anne; Salvayre, Robert; Auge, Nathalie; Pamplona, Reinald; Portero-Otin, Manuel
Hyperglycemia and glycation in diabetic complications.
ANTIOXIDANTS & REDOX SIGNALING 11 3071-3109. .
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Serrano, Jose; Jove, Mariona; Boada, Jordi; Josep Bellmunt, Maria; Pamplona, Reinald; Portero-Otin, Manuel
Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 388 443-449. .
Projects
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
- "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
- Gut microbiota profile after consumption of a patented fiber formulation
- ESTRES CELULAR Y DESLOCALIZACION DE FACTORES TRANSCRIPCIONALES EN LA FISIOPATOLOGIA DE LA ELA
