Directory
Jordi Calderó Pardo

Jordi Calderó Pardo

Degree: PhD

973 702 440
jordi.caldero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7373-2010

Groups

Publications

  • Salvany, S; Casanovas, A; Tarabal, O; Piedrafita, L; Hernandez, S; Santafe, M; Soto-Bernardini, MC; Caldero, J; Schwab, MH; Esquerda, JE

    Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair

    FASEB JOURNAL 33 7833-7851. .

    [doi:10.1096/fj.201802329R]

  • Cervero, C; Blasco, A; Tarabal, O; Casanovas, A; Piedrafita, L; Navarro, X; Esquerda, JE; Caldero, J

    Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn(2B/-) Mouse Model of Spinal Muscular Atrophy

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 77 577-597. .

    [doi:10.1093/jnen/nly033]

  • Narcis, JO; Tapia, O; Tarabal, O; Piedrafita, L; Caldero, J; Berciano, MT; Lafarga, M

    Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMN Delta 7 mouse model of SMA

    SCIENTIFIC REPORTS 8 9646-9646. .

    [doi:10.1038/s41598-018-27821-3]

  • Tapia, O; Narcis, JO; Riancho, J; Tarabal, O; Piedrafita, L; Caldero, J; Berciano, MT; Lafarga, M

    Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus

    NEUROBIOLOGY OF DISEASE 108 83-99. .

    [doi:10.1016/j.nbd.2017.08.004]

  • Casanovas, A; Salvany, S; Lahoz, V; Tarabal, O; Piedrafita, L; Sabater, R; Hernandez, S; Caldero, J; Esquerda, JE

    Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury

    SCIENTIFIC REPORTS 7 40155-40155. .

    [doi:10.1038/srep40155]

  • Cerveró C; Montull N; Tarabal O; Piedrafita L; Esquerda JE; Calderó J

    Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy

    NEUROTHERAPEUTICS 13 198-216. .

    [doi:10.1007/s13311-015-0399-x]

  • Gallart-Palau X; Tarabal O; Casanovas A; Sábado J; Correa FJ; Hereu M; Piedrafita L; Calderó J; Esquerda JE

    Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to alpha-motoneurons and altered during motoneuron diseases

    FASEB JOURNAL 28 3618-3632. .

    [doi:10.1096/fj.13-248583]

  • Tarabal O; Caraballo-Miralles V; Cardona-Rossinyol A; Correa FJ; Olmos G; Lladó J; Esquerda JE; Calderó J

    Mechanisms Involved in Spinal Cord Central Synapse Loss in a Mouse Model of Spinal Muscular Atrophy

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 73 519-535. .

    [doi:10.1097/NEN.0000000000000074]

  • Sabado, Javier; Casanovas, Anna; Tarabal, Olga; Hereu, Marta; Piedrafita, Ldia; Caldero, Jordi; Esquerda, Josep E.

    Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis

    BioMed Research International 2014 -. .

    [doi:10.1155/2014/852163]

  • Dachs E; Piedrafita L; Hereu M; Esquerda JE; Calderó J

    CHRONIC TREATMENT WITH LITHIUM DOES NOT IMPROVE NEUROMUSCULAR PHENOTYPE IN A MOUSE MODEL OF SEVERE SPINAL MUSCULAR ATROPHY

    NEUROSCIENCE 250 417-433. .

    [doi:10.1016/j.neuroscience.2013.07.026]

  • Dachs, Elisabet; Hereu, Marta; Piedrafita, Lidia; Casanovas, Anna; Caldero, Jordi; Esquerda, Josep E.

    Defective neuromuscular junction organization and postnatal myogenesis in mice with severe spinal muscular atrophy.

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 70 444-461. .

    [doi:10.1097/NEN.0b013e31821cbd8b]

  • Hernandez, Sara; Texido, Laura; Caldero, Jordi; Ciutat, Dolors; Piedrafita, Lidia; Casanovas, Anna; Blasi, Joan; Solsona, Carles; Povedano, Monica; Rojas, Ricardo; Illa, Isabel; Caress, James; Prevette, David; Oppenheim, Ronald W.; Milligan, Carol; Esquerda, Josep E.

    Increased intramuscular nerve branching and inhibition of programmed cell death of chick embryo motoneurons by immunoglobulins from patients with motoneuron disease.

    Journal Of Neuroimmunology 229 157-168. .

    [doi:10.1016/j.jneuroim.2010.07.028]

Projects

  • Mecanismos subyacentes a la patología del circuito motor y la miopatía primaria en atrofia muscular espinal: identificación de dianas para terapias combinadas con nusinersen
  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • El sistema NRG1-ErbBs en la arquitectura molecular de las sinapsis aferentes de tipo C y su significado en las enfermedades de la motoneurona
  • Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
  • Caracterización fenotípica y estrategias terapéuticas en modelos murinos de atrofia muscular espinal (AME)
  • Mecanismos de neurodegeneración en modelos animales de atrofia muscular espinal y ensayos de neuroprotección con litio
  • Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental
  • Mecanismos de degeneración excitotóxica en las motoneuronas espinales y efecto neuroprotector del litio: relevancia en el contexto de la esclerosis lateral amiotrófica