Molecular Oncology
The main interest of our laboratory is the study of molecular events underlying the oncogenic process, especially in colorectal, gastric and head-and-neck cancer. Gaining a deeper understanding of the molecular mechanisms responsible for the tumorigenic process is essential to improve the diagnosis and treatment of these patients. We are also interested in the identification of novel biomarkers capable of predicting therapy response, thus contributing to treatment personalization for colorectal cancer patients. Finally, we explore novel therapeutic options for microvillus inclusion disease (MVID), a rare life-threatening intestinal disease.
Featured publications
Fourniols, T; Maggio, V; Rafael, D; Colaco, A; García Vidal E; Lopes, A; Schwartz, S; Martinez-Barriocanal, A; Preat, V; Arango, D
Colorectal cancer inhibition by BET inhibitor JQ1 is MYC-independent and not improved by nanoencapsulation.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 171 39-49. .
Giralt, I; Gallo-Oller, G; Navarro, N; Zarzosa, P; Pons, G; Magdaleno, A; Segura, MF; Sabado, C; Hladun, R; Arango, D; Sánchez de Toledo J; Moreno, L; Gallego, S; Roma, J
Dickkopf-1 Inhibition Reactivates Wnt/ß-Catenin Signaling in Rhabdomyosarcoma, Induces Myogenic Markers In Vitro and Impairs Tumor Cell Survival In Vivo.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 -. .
Martinez-Barriocanal, A; Arango, D; Dopeso, H
PVT1 Long Non-coding RNA in Gastrointestinal Cancer.
Frontiers in oncology 10 38-38. .
Responsable/s de grup
Diego Arango Del Corro
Biomedicine I / Biomedicina I
4th floor / 4a planta
Lab b4.8