Directori de persones
Joaquim Ros Salvador

Joaquim Ros Salvador

Grau: Doctor/a

973 702 275
joaquim.ros(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7507-2010

Grups

Publicacions

  • Alba Sorolla, M.; Jose Rodriguez-Colman, Clara Nierga M.; Reverter-Branchat, Gemma; Arenas, Alicia; Tamarit, Jordi; Ros, Joaquim; Cabiscol, Elisa

    Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.

    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 510 27-34. .

    [doi:10.1016/j.abb.2011.04.002]

  • Moreno-Cermeno, Armando; Obis, Elia; Belli, Gemma; Cabiscol, Elisa; Ros, Joaquim; Tamarit, Jordi

    Frataxin depletion in yeast triggers up-regulation of iron transport systems before affecting iron-sulfur enzyme activities.

    Journal Of Biological Chemistry 285 41653-41664. .

    [doi:10.1074/jbc.M110.149443]

  • Irazusta, Veronica; Moreno-Cermeno, Armando; Cabiscol, Elisa; Tamarit, Jordi; Ros, Joaquim

    Proteomic Strategies for the analysis of Carbonyl Groups on Proteins.

    Current Protein & Peptide Science 11 652-658. .

    [doi:10.2174/138920310794557664]

  • Irazusta V; Moreno-Cermeño A; Cabiscol E; Tamarit J; Ros J

    Proteomic strategies for the analysis of carbonyl groups on proteins.

    Current Protein & Peptide Science 11 652-658. .

  • Jose Rodriguez-Colman, Maria; Reverter-Branchat, Gemma; Alba Sorolla, M.; Tamarit, Jordi; Ros, Joaquim; Cabiscol, Elisa

    The forkhead transcription factor Hcm1 promotes mitochondrial biogenesis and stress resistance in yeast.

    Journal Of Biological Chemistry 285 37092-37101. .

    [doi:10.1074/jbc.M110.174763]

  • Alba Sorolla, Ma; Jose Rodriguez-Colman, Ma; Tamarit, Jordi; Ortega, Zaira; Lucas, Jose J.; Ferrer, Isidre; Ros, Joaquim; Cabiscol, Elisa

    Protein oxidation in Huntington disease affects energy production and vitamin B6 metabolism.

    FREE RADICAL BIOLOGY AND MEDICINE 49 612-621. .

    [doi:10.1016/j.freeradbiomed.2010.05.016]

  • Gomez-Pastor, Rocio; Perez-Torrado, Roberto; Cabiscol, Elisa; Ros, Joaquim; Matallana, Emilia

    Reduction of oxidative cellular damage by overexpression of the thioredoxin TRX2 gene improves yield and quality of wine yeast dry active biomass.

    MICROBIAL CELL FACTORIES 9 9-9. .

    [doi:10.1186/1475-2859-9-9]

  • Irazusta, Veronica; Obis, Elia; Moreno-Cermeno, Armando; Cabiscol, Elisa; Ros, Joaquim; Tamarit, Jordi

    Yeast frataxin mutants display decreased superoxide dismutase activity crucial to promote protein oxidative damage.

    FREE RADICAL BIOLOGY AND MEDICINE 48 411-420. .

    [doi:10.1016/j.freeradbiomed.2009.11.010]

  • Herrero, Enrique; Ros, Joaquim; Belli, Gemma; Cabiscol, Elisa

    Redox control and oxidative stress in yeast cells.

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1780 1217-1235. .

    [doi:10.1016/j.bbagen.2007.12.004]

  • Sorolla, M. Alba; Reverter-Branchat, Gemma; Tamarit, Jordi; Ferrer, Isidre; Ros, Joaquim; Cabiscol, Elisa

    Proteomic and oxidative stress analysis in human brain samples of Huntington disease.

    FREE RADICAL BIOLOGY AND MEDICINE 45 667-678. .

    [doi:10.1016/j.freeradbiomed.2008.05.014]

  • Irazusta, Veronica; Moreno-Cermeno, Armando; Cabiscol, Elisa; Ros, Joaquim; Tamarit, Jordi

    Major targets of iron-induced protein oxidative damage in frataxin-deficient yeasts are magnesium-binding proteins.

    FREE RADICAL BIOLOGY AND MEDICINE 44 1712-1723. .

    [doi:10.1016/j.freeradbiomed.2008.01.014]

  • Reverter-Branchat, Gemma; Cabiscol, Elisa; Tamarit, Jordi; Sorolla, M. Alba; de la Torre, M. Angeles; Ros, Joaquim

    Chronological and replicative life-span extension in Saccharomyces cerevisiae by increased dosage of alcohol dehydrogenase 1.

    MICROBIOLOGY-SGM 153 3667-3676. .

    [doi:10.1099/mic.0.2007/009340-0]

Projectes

  • Uncovering the function of a conserved site in eukaryotic frataxins.
  • Desarrollo de la leriglitazona para el Síndrome de Rett y trastornos relacionados
  • Mecanismos de disfuncion mitocondrial y nuevas estrategias terapéuticas en modelos celulares y animales de Ataxia de Friedreich
  • Nuevo fármaco dirigido a la Ataxia de Friedreich
  • MithrAtaxia: Validació en laboratori dels efects protectors de mithramycin A por un us terapeutic en Ataxia de Friedreich
  • Targeting mitochondria in Friedreich Ataxia: molecular mechanisms and therapeutic approaches
  • Búsqueda de nuevas indicaciones terapéuticas en el ámbito de enfermedades neurodegenerativas y mitocondriales para el compuesto PPAR gamma agonista MIN-102
  • Effect of vitamin D in frataxin-deficient DRG neurons from rat and iPS cells obtained from FA patients
  • MODELOS CELULARES DE ATAXIA DE FRIEDREICH: BASES MOLECULARES DE LA PATOLOGIA E IDENTIFICACION DE BIOMARCADORES Y COMPUESTOS CON POTENCIAL TERAPEUTICO
  • Modelos celulares de ataxia de Friedreich: bases moleculares de la patología e identificación de biomarcadores y compuestos con potencial terapéutico
  • PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES
  • Análisis proteómico y funcional de los efectos del estrés oxidativo y la desregulación de la homeostasis del hierro en modelos celulares de ataxia de Friedreich