Directori de persones
Joaquim Ros Salvador

Joaquim Ros Salvador

Grau: Doctor/a

973 702 275
joaquim.ros(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7507-2010

Grups

Publicacions

  • Sanz-Alcázar, A; Portillo-Carrasquer, M; Delaspre, F; Pazos-Gil, M; Tamarit, J; Ros, J; Cabiscol, E

    Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3ß in the impairment of the NRF2 response

    Redox Biology 76 103339-103339. .

    [doi:10.1016/j.redox.2024.103339]

  • Alemany-Perna B; Tamarit J; Cabiscol E; Ros J

    Reply to: "Calcitriol in Friedreich Ataxia".

    MOVEMENT DISORDERS 39 1654-1655. .

    [doi:10.1002/mds.29971]

  • Alemany-Perna, B; Tamarit, J; Cabiscol, E; Delaspre, F; Miguela, A; Huertas-Pons, JM; Quiroga-Varela, A; Ruiz, MM; Dominguez, DL; Torrenta, L; Genis, D; Ros, J

    Calcitriol Treatment Is Safe and Increases Frataxin Levels in Friedreich Ataxia Patients

    MOVEMENT DISORDERS 39 1099-1108. .

    [doi:10.1002/mds.29808]

  • Sanz-Alcázar A; Britti E; Delaspre F; Medina-Carbonero M; Pazos-Gil M; Tamarit J; Ros J; Cabiscol E

    Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models.

    Cellular And Molecular Life Sciences 81 12-12. .

    [doi:10.1007/s00018-023-05064-4]

  • Medina-Carbonero, M; Sanz-Alcazar, A; Britti, E; Delaspre, F; Cabiscol, E; Ros, J; Tamarit, J

    Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations.

    Cellular And Molecular Life Sciences 79 74-74. .

    [doi:10.1007/s00018-021-04100-5]

  • Tamarit J; Britti E; Delaspre F; Medina-Carbonero M; Sanz-Alcázar A; Cabiscol E; Ros J

    Mitochondrial iron and calcium homeostasis in Friedreich ataxia.

    IUBMB LIFE 73 543-553. .

    [doi:10.1002/iub.2457]

  • Britti E; Delaspre F; Sanz A; Medina-Carbonero M; Llovera M; Purroy R; Mincheva-Tasheva S; Tamarit J; Ros J

    Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia.

    BIOCHEMICAL JOURNAL 478 1-20. .

    [doi:10.1042/BCJ20200331]

  • Britti, E; Delaspre, F; Tamarit, J; Ros, J

    Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na + /Ca 2+ Exchanger, NCLX, and Apoptosis.

    NEUROCHEMICAL RESEARCH 46 108-119. .

    [doi:10.1007/s11064-020-03020-3]

  • Rodríguez-Pascau L; Britti E; Calap-Quintana P; Dong YN; Vergara C; Delaspre F; Medina M; Tamarit J; Pallardó FV; Gonzalez-Cabo P; Ros J; Lynch DR; Martinell M; Pizcueta P

    PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia.

    NEUROBIOLOGY OF DISEASE 148 105162-105162. .

    [doi:10.1016/j.nbd.2020.105162]

  • Rodríguez Colman MJ; Ros J; Cabiscol E

    Mitochondrial Localization of the Yeast Forkhead Factor Hcm1.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 21 -. .

    [doi:10.3390/ijms21249574]

  • Purroy, R; Medina-Carbonero, M; Ros, J; Tamarit, J

    Frataxin-deficient cardiomyocytes present an altered thiol-redox state which targets actin and pyruvate dehydrogenase.

    Redox Biology 32 101520-101520. .

    [doi:10.1016/j.redox.2020.101520]

  • Britti, E; Ros, J; Esteras, N; Abramov, AY

    Tau inhibits mitochondrial calcium efflux and makes neurons vulnerable to calcium-induced cell death.

    Cell Calcium 86 102150-102150. .

    [doi:10.1016/j.ceca.2019.102150]

Projectes

  • Uncovering the function of a conserved site in eukaryotic frataxins.
  • Desarrollo de la leriglitazona para el Síndrome de Rett y trastornos relacionados
  • Mecanismos de disfuncion mitocondrial y nuevas estrategias terapéuticas en modelos celulares y animales de Ataxia de Friedreich
  • Nuevo fármaco dirigido a la Ataxia de Friedreich
  • MithrAtaxia: Validació en laboratori dels efects protectors de mithramycin A por un us terapeutic en Ataxia de Friedreich
  • Targeting mitochondria in Friedreich Ataxia: molecular mechanisms and therapeutic approaches
  • Búsqueda de nuevas indicaciones terapéuticas en el ámbito de enfermedades neurodegenerativas y mitocondriales para el compuesto PPAR gamma agonista MIN-102
  • Effect of vitamin D in frataxin-deficient DRG neurons from rat and iPS cells obtained from FA patients
  • MODELOS CELULARES DE ATAXIA DE FRIEDREICH: BASES MOLECULARES DE LA PATOLOGIA E IDENTIFICACION DE BIOMARCADORES Y COMPUESTOS CON POTENCIAL TERAPEUTICO
  • Modelos celulares de ataxia de Friedreich: bases moleculares de la patología e identificación de biomarcadores y compuestos con potencial terapéutico
  • PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES
  • Análisis proteómico y funcional de los efectos del estrés oxidativo y la desregulación de la homeostasis del hierro en modelos celulares de ataxia de Friedreich