Directorio de personas
Reinald Pamplona Gras

Reinald Pamplona Gras

Grado: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Grupos

Publicaciones

  • Ilieva, Ekaterina V.; Naudi, Alba; Kichev, Anton; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel

    Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease.

    FREE RADICAL BIOLOGY AND MEDICINE 48 1302-1310. .

    [doi:10.1016/j.freeradbiomed.2010.02.006]

  • Naudí A; Jové M; Ayala V; Portero-Otín M; Pamplona R

    Glicación de proteínas mitocondriales, estrés oxidativo y envejecimiento.

    Revista espanola de geriatria y gerontologia 45 156-166. .

    [doi:10.1016/j.regg.2010.02.001]

  • Martinez, Anna; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidre

    Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.

    BRAIN PATHOLOGY 20 281-297. .

    [doi:10.1111/j.1750-3639.2009.00326.x]

  • Terni, Beatrice; Boada, Jordi; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidro

    Mitochondrial ATP-synthase in the entorhinal cortex is a target of oxidative stress at stages I/II of Alzheimer's disease pathology.

    BRAIN PATHOLOGY 20 222-233. .

    [doi:10.1111/j.1750-3639.2009.00266.x]

  • Muntane, Gerard; Janue, Anna; Fernandez, Nuria; Odena, Maria Antonia; Oliveira, Eliandre; Boluda, Susana; Portero-Otin, Manuel; Naudi, Alba; Boada, Jordi; Pamplona, Reinald; Ferrer, Isidre

    Modification of brain lipids but not phenotype in alpha-synucleinopathy transgenic mice by long-term dietary n-3 fatty acids.

    NEUROCHEMISTRY INTERNATIONAL 56 318-328. .

    [doi:10.1016/j.neuint.2009.10.015]

  • Quiles, Jose L.; Pamplona, Reinald; Carmen Ramirez-Tortosa, M.; Naudi, Alba; Portero-Otin, Manuel; Araujo-Nepomuceno, Eduardo; Lopez-Frias, Magdalena; Battino, Maurizio; Ochoa, Julio J.

    Coenzyme Q addition to an n-6 PUFA-rich diet resembles benefits on age-related mitochondrial DNA deletion and oxidative stress of a MUFA-rich diet in rat heart.

    MECHANISMS OF AGEING AND DEVELOPMENT 131 38-47. .

    [doi:10.1016/j.mad.2009.11.004]

  • Fernandez, Liana Lisboa; Carmona, Marga; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Schroeder, Nadja; Ferrer, Isidro

    Effects of increased iron intake during the neonatal period on the brain of adult AbetaPP/PS1 transgenic mice.

    Journal Of Alzheimers Disease 19 1069-1080. .

    [doi:10.3233/JAD-2010-1304]

  • Negre-Salvayre, Anne; Salvayre, Robert; Auge, Nathalie; Pamplona, Reinald; Portero-Otin, Manuel

    Hyperglycemia and glycation in diabetic complications.

    ANTIOXIDANTS & REDOX SIGNALING 11 3071-3109. .

    [doi:10.1089/ars.2009.2484]

  • Kichev, Anton; Ilieva, Ekaterina V.; Pinol-Ripoll, Gerard; Podlesniy, Petar; Ferrer, Isidro; Portero-Otin, Manuel; Pamplona, Reinald; Espinet, Carme

    Cell death and learning impairment in mice caused by in vitro modified pro-NGF can be related to its increased oxidative modifications in Alzheimer disease.

    AMERICAN JOURNAL OF PATHOLOGY 175 2574-2585. .

    [doi:10.2353/ajpath.2009.090018]

  • Caro, Pilar; Gomez, Jose; Sanchez, Ines; Naudi, Alba; Ayala, Victoria; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

    Forty percent methionine restriction decreases mitochondrial oxygen radical production and leak at complex I during forward electron flow and lowers oxidative damage to proteins and mitochondrial DNA in rat kidney and brain mitochondria.

    REJUVENATION RESEARCH 12 421-434. .

    [doi:10.1089/rej.2009.0902]

  • Serrano, Jose; Jove, Mariona; Boada, Jordi; Josep Bellmunt, Maria; Pamplona, Reinald; Portero-Otin, Manuel

    Dietary antioxidants interfere with Amplex Red-coupled-fluorescence assays.

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 388 443-449. .

    [doi:10.1016/j.bbrc.2009.08.041]

  • Caro, Pilar; Gomez, Jose; Sanchez, Ines; Garcia, Ruben; Lopez-Torres, Monica; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo

    Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver.

    Biogerontology 10 579-592. .

    [doi:10.1007/s10522-008-9200-4]

Proyectos

  • Metabolismo de eter lípidos y envejecimiento humano
  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement
  • CONVOCATORIA D'AJUTS PER A PERSONAL PREDOCTORAL DEL IRBLLEIDA "FUNDACIO LA CAIXA"