Directorio de personas
Reinald Pamplona Gras

Reinald Pamplona Gras

Grado: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Grupos

Publicaciones

  • Gomez, Jose; Caro, Pilar; Sanchez, Ines; Naudi, Alba; Jove, Mariona; Portero-Otin, Manuel; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

    Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart.

    JOURNAL OF BIOENERGETICS AND BIOMEMBRANES 41 309-321. .

    [doi:10.1007/s10863-009-9229-3]

  • Pamplona R

    La vida humana ante el proceso de envejecimiento.

    Revista espanola de geriatria y gerontologia 44 119-119. .

    [doi:10.1016/j.regg.2009.03.002]

  • Martinez, Anna; Carmona, Margarita; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Ferrer, Isidre

    Type-dependent oxidative damage in frontotemporal lobar degeneration: cortical astrocytes are targets of oxidative damage (vol 67, pg 1122, 2008)

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 68 112-112. .

  • Martinez, Anna; Carmona, Margarita; Portero-Otin, Manuel; Naudi, Alba; Pamplona, Reinald; Ferrer, Isidre

    Type-dependent oxidative damage in frontotemporal lobar degeneration: cortical astrocytes are targets of oxidative damage.

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 67 1122-1136. .

    [doi:10.1097/NEN.0b013e31818e06f3]

  • Pamplona, Reinald; Naudi, Alba; Gavin, Rosalina; Pastrana, Miguel A.; Sajnani, Gustavo; Ilieva, Ekaterina V.; Antonio del Rio, Jose; Portero-Otin, Manuel; Ferrer, Isidre; Requena, Jesus R.

    Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease.

    FREE RADICAL BIOLOGY AND MEDICINE 45 1159-1166. .

    [doi:10.1016/j.freeradbiomed.2008.07.009]

  • Pamplona, Reinald

    Membrane phospholipids, lipoxidative damage and molecular integrity: a causal role in aging and longevity.

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1777 1249-1262. .

    [doi:10.1016/j.bbabio.2008.07.003]

  • Fourcade, Stephane; Lopez-Erauskin, Jone; Galino, Jorge; Duval, Carine; Naudi, Alba; Jove, Mariona; Kemp, Stephan; Villarroya, Francesc; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel; Pujol, Aurora

    Early oxidative damage underlying neurodegeneration in X-adrenoleukodystrophy.

    HUMAN MOLECULAR GENETICS 17 1762-1773. .

    [doi:10.1093/hmg/ddn085]

  • Caro, Pilar; Gomez, Jose; Lopez-Torres, Monica; Sanchez, Ines; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo

    Effect of every other day feeding on mitochondrial free radical production and oxidative stress in mouse liver.

    REJUVENATION RESEARCH 11 621-629. .

    [doi:10.1089/rej.2008.0704]

  • Caro, Pilar; Gomez, Jose; Lopez-Torres, Monica; Sanchez, Ines; Naudi, Alba; Jove, Mariona; Pamplona, Reinald; Barja, Gustavo

    Forty percent and eighty percent methionine restriction decrease mitochondrial ROS generation and oxidative stress in rat liver.

    Biogerontology 9 183-196. .

    [doi:10.1007/s10522-008-9130-1]

  • Portero-Otin, Manuel; Pamplona, Reinald; Boada, Jordi; Jove, Mariona; Gonzalo, Hugo; Buleon, Marie; Linzc, Wolfgang; Schaefer, Stefan; Tack, Ivan; Girolami, Jean-Pierre

    Inhibition of renin angiotensin system decreases renal protein oxidative damage in diabetic rats.

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 368 528-535. .

    [doi:10.1016/j.bbrc.2008.01.101]

  • Pamplona R; Ilieva E; Ayala V; Bellmunt MJ; Cacabelos D; Dalfo E; Ferrer I; Portero-Otin M

    Maillard reaction versus other nonenzymatic modifications in neurodegenerative processes.

    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1126 315-319. .

    [doi:10.1196/annals.1433.014]

  • Ilieva, Ekaterina V.; Ayala, VictorRia; Jove, Mariona; Dalfo, Esther; Cacabelos, Daniel; Povedano, Monica; Bellmunt, Maria Josep; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel

    Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis.

    BRAIN 130 3111-3123. .

    [doi:10.1093/brain/awm190]

Proyectos

  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement
  • CONVOCATORIA D'AJUTS PER A PERSONAL PREDOCTORAL DEL IRBLLEIDA "FUNDACIO LA CAIXA"
  • Papel de la composicion de membrana en el envejecimiento y la determinacion de la longevidad: una aproximacion lipidomica y proteomica