Jordi Calderó Pardo
Grado: Doctor/a
973 702 440
jordi.caldero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/A-7373-2010
Publicaciones
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Cervero, C; Blasco, A; Tarabal, O; Casanovas, A; Piedrafita, L; Navarro, X; Esquerda, JE; Caldero, J
Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn(2B/-) Mouse Model of Spinal Muscular Atrophy
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 77 577-597. .
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Narcis, JO; Tapia, O; Tarabal, O; Piedrafita, L; Caldero, J; Berciano, MT; Lafarga, M
Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMN Delta 7 mouse model of SMA
SCIENTIFIC REPORTS 8 9646-9646. .
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Tapia, O; Narcis, JO; Riancho, J; Tarabal, O; Piedrafita, L; Caldero, J; Berciano, MT; Lafarga, M
Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus
NEUROBIOLOGY OF DISEASE 108 83-99. .
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Casanovas, A; Salvany, S; Lahoz, V; Tarabal, O; Piedrafita, L; Sabater, R; Hernandez, S; Caldero, J; Esquerda, JE
Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury
SCIENTIFIC REPORTS 7 40155-40155. .
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Cerveró C; Montull N; Tarabal O; Piedrafita L; Esquerda JE; Calderó J
Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy
NEUROTHERAPEUTICS 13 198-216. .
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Gallart-Palau X; Tarabal O; Casanovas A; Sábado J; Correa FJ; Hereu M; Piedrafita L; Calderó J; Esquerda JE
Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to alpha-motoneurons and altered during motoneuron diseases
FASEB JOURNAL 28 3618-3632. .
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Tarabal O; Caraballo-Miralles V; Cardona-Rossinyol A; Correa FJ; Olmos G; Lladó J; Esquerda JE; Calderó J
Mechanisms Involved in Spinal Cord Central Synapse Loss in a Mouse Model of Spinal Muscular Atrophy
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 73 519-535. .
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Sabado, Javier; Casanovas, Anna; Tarabal, Olga; Hereu, Marta; Piedrafita, Ldia; Caldero, Jordi; Esquerda, Josep E.
Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis
BioMed Research International 2014 -. .
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Dachs E; Piedrafita L; Hereu M; Esquerda JE; Calderó J
CHRONIC TREATMENT WITH LITHIUM DOES NOT IMPROVE NEUROMUSCULAR PHENOTYPE IN A MOUSE MODEL OF SEVERE SPINAL MUSCULAR ATROPHY
NEUROSCIENCE 250 417-433. .
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Dachs, Elisabet; Hereu, Marta; Piedrafita, Lidia; Casanovas, Anna; Caldero, Jordi; Esquerda, Josep E.
Defective neuromuscular junction organization and postnatal myogenesis in mice with severe spinal muscular atrophy.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 70 444-461. .
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Hernandez, Sara; Texido, Laura; Caldero, Jordi; Ciutat, Dolors; Piedrafita, Lidia; Casanovas, Anna; Blasi, Joan; Solsona, Carles; Povedano, Monica; Rojas, Ricardo; Illa, Isabel; Caress, James; Prevette, David; Oppenheim, Ronald W.; Milligan, Carol; Esquerda, Josep E.
Increased intramuscular nerve branching and inhibition of programmed cell death of chick embryo motoneurons by immunoglobulins from patients with motoneuron disease.
Journal Of Neuroimmunology 229 157-168. .
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Caldero, J.; Brunet, N.; Tarabal, O.; Piedrafita, L.; Hereu, M.; Ayala, V.; Esquerda, J. E.
Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord.
NEUROSCIENCE 165 1353-1369. .
Proyectos
- Mecanismos subyacentes a la patología del circuito motor y la miopatía primaria en atrofia muscular espinal: identificación de dianas para terapias combinadas con nusinersen
- Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
- El sistema NRG1-ErbBs en la arquitectura molecular de las sinapsis aferentes de tipo C y su significado en las enfermedades de la motoneurona
- Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
- Caracterización fenotípica y estrategias terapéuticas en modelos murinos de atrofia muscular espinal (AME)
- Mecanismos de neurodegeneración en modelos animales de atrofia muscular espinal y ensayos de neuroprotección con litio
- Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental
- Mecanismos de degeneración excitotóxica en las motoneuronas espinales y efecto neuroprotector del litio: relevancia en el contexto de la esclerosis lateral amiotrófica