Directorio de personas
Mario Encinas Martin

Mario Encinas Martin

Grado: Doctor/a

973 70 2943 / 2951
mario.encinas(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-5600-2009

Grupos

Publicaciones

  • Podlesniy, P; Kichev, A; Pedraza, C; Saurat, J; Encinas, M; Perez, B; Ferrer, I; Espinet, C

    Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis.

    AMERICAN JOURNAL OF PATHOLOGY 169 119-131. .

    [doi:10.2353/ajpath.2006.050787]

  • Jain, S; Encinas, M; Johnson, EM; Milbrandt, J

    Critical and distinct roles for key RET tyrosine docking sites in renal development

    GENES & DEVELOPMENT 20 321-333. .

    [doi:10.1101/gad.1387206]

  • Yuste, VJ; Sanchez-Lopez, I; Sole, C; Moubarak, RS; Bayascas, JR; Dolcet, X; Encinas, M; Susin, SA; Comella, JX

    The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis.

    Journal Of Biological Chemistry 280 35670-35683. .

    [doi:10.1074/jbc.M504015200]

  • Jain, S; Naughton, CK; Yang, M; Strickland, A; Vij, K; Encinas, M; Golden, J; Gupta, A; Heuckeroth, R; Johnson, EM; Milbrandt, J

    Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis

    Development 131 5503-5513. .

    [doi:10.1242/dev.01421]

  • Encinas, M; Crowder, RJ; Milbrandt, J; Johnson, EM

    Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival

    Journal Of Biological Chemistry 279 18262-18269. .

    [doi:10.1074/jbc.M400505200]

  • Liu, YH; Encinas, M; Comella, JX; ALDEA, M; Gallego, C

    Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells.

    MOLECULAR AND CELLULAR BIOLOGY 24 2662-2672. .

    [doi:10.1128/MCB.24.7.2662-2672.2004]

  • Llovera, M; de Pablo, Y; Egea, J; Encinas, M; Peiro, S; Martin-Zanca, D; Rocamora, N; Comella, JX

    Trk is a calmodulin-binding protein: implications for receptor processing.

    JOURNAL OF NEUROCHEMISTRY 88 422-433. .

    [doi:10.1046/j.1471-4159.2003.02178.x]

  • Tsui-Pierchala, BA; Encinas, M; Milbrandt, J; Johnson, EM

    Lipid rafts in neuronal signaling and function

    TRENDS NEUROSCI 25 412-417. .

    [doi:10.1016/S0166-2236(02)02215-4]

  • Yuste, VJ; Sanchez-Lopez, I; Sole, C; Encinas, M; Bayascas, JR; Boix, J; Comella, JX

    The prevention of the staurosporine-induced apoptosis by Bcl-X-L, but not by Bcl-2 or caspase inhibitors, allows the extensive differentiation of human neuroblastoma cells

    JOURNAL OF NEUROCHEMISTRY 80 126-139. .

    [doi:10.1046/j.0022-3042.2001.00695.x]

  • Egea, J; Espinet, C; Soler, RM; Dolcet, X; Yuste, VJ; Encinas, M; Iglesias, M; Rocamora, N; Comella, JX

    Neuronal survival induced by neurotrophins requires calmodulin.

    JOURNAL OF CELL BIOLOGY 154 585-597. .

    [doi:10.1083/jcb.200101023]

  • Encinas, M; Tansey, MG; Tsui-Pierchala, BA; Comella, JX; Milbrandt, J; Johnson, EM

    c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

    JOURNAL OF NEUROSCIENCE 21 1464-1472. .

  • Encinas, M; Iglesias, M; Liu, YH; Wang, HY; Muhaisen, A; Cena, V; Gallego, C; Comella, JX

    Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells.

    JOURNAL OF NEUROCHEMISTRY 75 991-1003. .

    [doi:10.1046/j.1471-4159.2000.0750991.x]

Proyectos

  • Exploring vulnerabilities of medullary thyroid carcinoma beyond Ret kinase inhibition
  • INVESTIGO 2022: Senyalització oncogènica i del desenvolupament
  • Mecanismos moleculares y efectos biológicos de la senescencia celular mediada por Sprouty
  • Definiendo el papel de las proteínas Sprouty en la senescencia celular
  • Disección de la función de Spry1 mediante deleción genética y análisis mutacional
  • A ROLE FOR RET SIGNALING IN SMITH-LEMLI-OPITZ SYNDROME
  • Regulación de la señalización de RET por SPROUTY mecanismos moleculares
  • Anàlisis de las vias de señalización relevantes para la supervivència neuronal, papel de B-raf
  • Entendiendo la regulación de la señalización por FGF por las proteínas Sprouty