Directory
Reinald Pamplona Gras

Reinald Pamplona Gras

Degree: PhD

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Groups

Publications

  • Portero-Otin, M; Pamplona, R; Bellmunt, MJ; Ruiz, MC; Prat, J; Salvayre, R; Negre-Salvayre, A

    Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

    Diabetes 51 1535-1542. .

    [doi:10.2337/diabetes.51.5.1535]

  • Pamplona R; Barja G; PORTERO OTIN, MANUEL

    Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: a homeoviscous-longevity adaptation?

    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 959 475-490. .

  • Pamplona R; PORTERO OTIN, MANUEL; Bellmun MJ; Gredilla R; Barja G

    Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.

    FREE RADICAL RESEARCH 36 47-54. .

  • Doñate T; Herreros A; Martinez E; Martinez J; Andrés E; Cabezas A; Ortiz A; de Prado A; Pou JM; Pamplona R; Portero Otin M; Bellmunt MJ

    Protein oxidative stress in dialysis patients.

    Advances In Peritoneal Dialysis. Conference On Peritoneal Dialysis 18 15-17. .

  • Pamplona, R; Portero-Otin, M; Bellmunt, MJ; Gredilla, R; Barja, G

    Aging increases N(epsilon)-(carboxymethyl)lysine and caloric restriction decreases N(epsilon)-(carboxyethyl)lysine and N(epsilon)-(malondialdehyde)lysine in rat heart mitochondrial proteins

    FREE RADICAL RESEARCH 36 47-54. .

    [doi:10.1080/10715760290001281]

  • Portero-Otin, M; Bellmunt, MJ; Ruiz, MC; Barja, G; Pamplona, R

    Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipid classes in mammals to their maximum life span potential.

    Lipids 36 491-498. .

    [doi:10.1007/s11745-001-0748-y]

  • Gredilla, R; Lopez Torres, M; Portero-Otin, M; Pamplona, R; Barja, G

    Influence of hyper- and hypothyroidism on lipid peroxidation, unsaturation of phospholipids, glutathione system and oxidative damage to nuclear and mitochondrial DNA in mice skeletal muscle.

    MOL CELL BIOCHEM 221 41-48. .

    [doi:10.1023/A:1010930110382]

  • Herrero, A; Portero-Otin, M; Bellmunt, MJ; Pamplona, R; Barja, G

    Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage.

    MECHANISMS OF AGEING AND DEVELOPMENT 122 427-443. .

    [doi:10.1016/S0047-6374(01)00214-7]

  • Pamplona, R; Portero-Otin, M; Riba, D; Requena, JR; Thorpe, SR; Lopez-Torres, M; Barja, G

    Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 55 286-291. .

  • Ruiz, MC; Bellmunt, MJ; Pamplona, R; Lafarga, A; Porterootin, M

    Protein oxidative damage is selectively increased in kidney mitochondria of rats with streptozotocin-induced diabetes

    Diabetes 49 1203-1203. .

  • Portero-Otin, M; Pamplona, R; Bellmunt, MJ; Ruiz, C; Lafarga, A; Salvayre, R; Negre-Salvayre, A

    Maillard-reaction derived oxoaldehydes inhibit epidermal-growth factor receptor activity in human cultured endothelial cells

    Diabetes 49 1395-1395. .

  • Pamplona, R; Portero-Otin, M; Ruiz, C; Gredilla, R; Herrero, A; Barja, G

    Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals.

    MECHANISMS OF AGEING AND DEVELOPMENT 112 169-183. .

    [doi:10.1016/S0047-6374(99)00045-7]

Projects

  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement
  • CONVOCATORIA D'AJUTS PER A PERSONAL PREDOCTORAL DEL IRBLLEIDA "FUNDACIO LA CAIXA"
  • Papel de la composicion de membrana en el envejecimiento y la determinacion de la longevidad: una aproximacion lipidomica y proteomica