Directory
Reinald Pamplona Gras

Reinald Pamplona Gras

Degree: PhD

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Publications

  • Sanchez-Roman, Ines; Gomez, Jose; Naudi, Alba; Ayala, Victoria; Portero-Otin, Manuel; Lopez-Torres, Monica; Pamplona, Reinald; Barja, Gustavo

    The ß-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage, and increases extracellular signal-regulated kinase signaling in the heart of C57BL/6 mice.

    REJUVENATION RESEARCH 13 683-693. .

    [doi:10.1089/rej.2010.1062]

  • Negre-Salvayre, Anne; Auge, Nathalie; Ayala, Victoria; Basaga, Huveyda; Boada, Jordi; Brenke, Rainer; Chapple, Sarah; Cohen, Guy; Feher, Janos; Grune, Tilman; Lengyel, Gabriella; Mann, Giovanni E.; Pamplona, Reinald; Poli, Giuseppe; Portero-Otin, Manuel; Riahi, Yael; Salvayre, Robert; Sasson, Shlomo; Serrano, Jose; Shamni, Ofer; Siems, Werner; Siow, Richard C. M.; Wiswedel, Ingrid; Zarkovic, Kamelija; Zarkovic, Neven

    Pathological aspects of lipid peroxidation.

    FREE RADICAL RESEARCH 44 1125-1171. .

    [doi:10.3109/10715762.2010.498478]

  • Jacobson, Jake; Lambert, Adrian J.; Portero-Otin, Manuel; Pamplona, Reinald; Magwere, Tapiwanashe; Miwa, Satomi; Driege, Yasmine; Brand, Martin D.; Partridge, Linda

    Biomarkers of aging in Drosophila.

    AGING CELL 9 466-477. .

    [doi:10.1111/j.1474-9726.2010.00573.x]

  • Hiona, Asimina; Sanz, Alberto; Kujoth, Gregory C.; Pamplona, Reinald; Seo, Arnold Y.; Hofer, Tim; Someya, Shinichi; Miyakawa, Takuya; Nakayama, Chie; Samhan-Arias, Alejandro K.; Servais, Stephane; Barger, Jamie L.; Portero-Otin, Manuel; Tanokura, Masaru; Prolla, Tomas A.; Leeuwenburgh, Christiaan

    Mitochondrial DNA mutations induce mitochondrial dysfunction, apoptosis and sarcopenia in skeletal muscle of mitochondrial DNA mutator mice.

    PLOS ONE 5 -. .

    [doi:10.1371/journal.pone.0011468]

  • Pamplona R

    Restricción dietaria y envejecimiento: ¿una cuestión de calorías?

    Revista espanola de geriatria y gerontologia 45 232-238. .

    [doi:10.1016/j.regg.2010.05.001]

  • Jove, Mariona; Serrano, Jose C. E.; Bellmunt, Maria Josep; Cassanye, Anna; Angles, Neus; Reguant, Jordi; Morello, Jose R.; Pamplona, Reinald; Portero-Otin, Manuel

    When cholesterol is not cholesterol: a note on the enzymatic determination of its concentration in model systems containing vegetable extracts.

    LIPIDS IN HEALTH AND DISEASE 9 65-65. .

    [doi:10.1186/1476-511X-9-65]

  • Serrano, Jose; Cipak, Ana; Boada, Jordi; Gonzalo, Hugo; Cacabelos, Daniel; Cassanye, Anna; Pamplona, Reinald; Zarkovic, Neven; Portero-Otin, Manuel

    Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects.

    ACTA BIOCHIMICA POLONICA 57 193-198. .

  • Sanz, Alberto; Soikkeli, Mikko; Portero-Otin, Manuel; Wilson, Angela; Kemppainen, Esko; McIlroy, George; Ellila, Simo; Kemppainen, Kia K.; Tuomela, Tea; Lakanmaa, Matti; Kiviranta, Essi; Stefanatos, Rhoda; Dufour, Eric; Hutz, Bettina; Naudi, Alba; Jove, Mariona; Zeb, Akbar; Vartiainen, Suvi; Matsuno-Yagi, Akemi; Yagi, Takao; Rustin, Pierre; Pamplona, Reinald; Jacobs, Howard T.

    Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107 9105-9110. .

    [doi:10.1073/pnas.0911539107]

  • Fourcade, Stephane; Ruiz, Montserrat; Guilera, Cristina; Hahnen, Eric; Brichta, Lars; Naudi, Alba; Portero-Otin, Manuel; Dacremont, Georges; Cartier, Nathalie; Wanders, Ronald; Kemp, Stephan; Mandel, Jean Louis; Wirth, Brunhilde; Pamplona, Reinald; Aubourg, Patrick; Pujol, Aurora

    Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.

    HUMAN MOLECULAR GENETICS 19 2005-2014. .

    [doi:10.1093/hmg/ddq082]

  • Ilieva, Ekaterina V.; Naudi, Alba; Kichev, Anton; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel

    Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease.

    FREE RADICAL BIOLOGY AND MEDICINE 48 1302-1310. .

    [doi:10.1016/j.freeradbiomed.2010.02.006]

  • Naudí A; Jové M; Ayala V; Portero-Otín M; Pamplona R

    Glicación de proteínas mitocondriales, estrés oxidativo y envejecimiento.

    Revista espanola de geriatria y gerontologia 45 156-166. .

    [doi:10.1016/j.regg.2010.02.001]

  • Martinez, Anna; Portero-Otin, Manuel; Pamplona, Reinald; Ferrer, Isidre

    Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates.

    BRAIN PATHOLOGY 20 281-297. .

    [doi:10.1111/j.1750-3639.2009.00326.x]

Projects

  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement
  • CONVOCATORIA D'AJUTS PER A PERSONAL PREDOCTORAL DEL IRBLLEIDA "FUNDACIO LA CAIXA"
  • Papel de la composicion de membrana en el envejecimiento y la determinacion de la longevidad: una aproximacion lipidomica y proteomica