![Manuel Portero Otin](/media/upload/cache/130386_a115x115.jpg)
Manuel Portero Otin
Degree: PhD
973 702 408
manuel.portero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/B-7122-2009
Groups
Publications
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Berdún R; Obis È; Mota-Martorell N; Bassols A; Valent D; Serrano JCE; Martín-Garí M; Rodríguez-Palmero M; Moreno-Muñoz JA; Tibau J; Quintanilla R; Pamplona R; Portero-Otín M; Jové M
High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage.
Antioxidants 13 -. .
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Sol, J; Ortega-Bravo, M; Portero-Otín, M; Pinol-Ripoll, G; Ribas-Ripoll, V; Artigues-Barberà, E; Butí, M; Pamplona, R; Jové, M
Human lifespan and sex-specific patterns of resilience to disease: a retrospective population-wide cohort study
BMC MEDICINE 22 17-17. .
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Jové, M; Mota-Martorell, N; Fernàndez-Bernal, A; Portero-Otin, M; Barja, G; Pamplona, R
Phenotypic molecular features of long-lived animal species
FREE RADICAL BIOLOGY AND MEDICINE 208 728-747. .
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Serrano, JCE; Castro-Boque, E; Garcia-Carrasco, A; Moran-Valero, MI; Gonzalez-Hedstrom, D; Bermudez-Lopez, M; Valdivielso, JM; Espinel, AE; Portero-Otin, M
Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial
Nutrients 15 -. .
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Purroy, F; Ois, A; Jove, M; Arque, G; Sol, J; Mauri-Capdevila, G; Rodriguez-Campello, A; Pamplona, R; PORTERO, M; Roquer, J
Lipidomic signature of stroke recurrence after transient ischemic attack
SCIENTIFIC REPORTS 13 13706-13706. .
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Torres P; Pamplona R; Portero-Otin M
Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes.
Neural Regeneration Research 18 1725-1726. .
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Bernal AF; Mota N; Pamplona R; Area-Gomez E; Portero-Otin M
Hakuna MAM-Tata: Investigating the role of mitochondrial-associated membranes in ALS.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1869 166716-166716. .
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Brewer, MK; Torres, P; Ayala, V; Portero-Otin, M; Pamplona, R; Andres-Benito, P; Ferrer, I; Guinovart, JJ; Duran, J
Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis
JOURNAL OF NEUROCHEMISTRY 168 744-759. .
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Portero-Otin, M; de la Maza, MP; Uribarri, J
Dietary Advanced Glycation End Products: Their Role in the Insulin Resistance of Aging
Cells 12 -. .
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Sol J; Obis È; Mota-Martorell N; Pradas I; Galo-Licona JD; Martin-Garí M; Fernández-Bernal A; Ortega-Bravo M; Mayneris-Perxachs J; Borrás C; Viña J; de la Fuente M; Mate I; Biarnes C; Pedraza S; Vilanova JC; Brugada R; Ramos R; Serena J; Ramió-Torrentà L; Pineda V; Daunis-I-Estadella P; Thió-Henestrosa S; Barretina J; Garre-Olmo J; Portero-Otin M; Fernández-Real JM; Puig J; Jové M; Pamplona R
Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.
AGING CELL 22 -. .
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Planas-Serra L; Launay N; Goicoechea L; Heron B; Jou C; Juliá-Palacios N; Ruiz M; Fourcade S; Casasnovas C; De La Torre C; Gelot A; Marsal M; Loza-Alvarez P; García-Cazorla À; Fatemi A; Ferrer I; Portero-Otin M; Area-Gómez E; Pujol A
Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity.
JOURNAL OF CLINICAL INVESTIGATION 133 -. .
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Obis, E; Sol, J; Andres-Benito, P; Martin-Gari, M; Mota-Martorell, N; Galo-Licona, JD; Piñol-Ripoll G; Portero-Otin, M; Ferrer, I; Jove, M; Pamplona, R
Lipidomic Alterations in the Cerebral Cortex and White Matter in Sporadic Alzheimer's Disease.
Aging and Disease 14 1887-1916. .
Projects
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
- "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
- Gut microbiota profile after consumption of a patented fiber formulation
- ESTRES CELULAR Y DESLOCALIZACION DE FACTORES TRANSCRIPCIONALES EN LA FISIOPATOLOGIA DE LA ELA