![Manuel Portero Otin](/media/upload/cache/130386_a115x115.jpg)
Manuel Portero Otin
Degree: PhD
973 702 408
manuel.portero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/B-7122-2009
Groups
Publications
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Pamplona R; Requena JR; Portero-Otín M; Prat J; Thorpe SR; Bellmunt MJ
Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals--evidence for intracellular lipid glycoxidation.
European Journal Of Biochemistry 255 685-689. .
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Portero-Otin, A; Pamplona, R; Riba, D; Ruiz, C; Lafarga, MA; Bellmunt, MJ; Prat, J
Evidence against a diabetes induced generalized increase of oxidative damage in liver cytosolic proteins
Diabetologia 41 1243-1243. .
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Pamplona, R; Requena, JR; Portero-Otin, M; Prat, J; Thorpe, SR; Bellmunt, MJ
Carboxymethylated phosphatidylethanolamine in mitochondrial membranes of mammals - Evidence for intracellular lipid glycoxidation
European Journal Of Biochemistry 255 685-689. .
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PorteroOtin, M; Pamplona, R; Bellmunt, MJ; Bergua, M; Prat, J
Glycaemic control and in vivo non-oxidative Maillard reaction: urinary excretion of pyrraline in diabetes patients.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 27 767-773. .
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PORTERO OTIN, MANUEL; Pamplona R; Bellmunt MJ; Bergua M; Nagaraj RH; Prat J
Urinary pyrraline as a biochemical marker of non-oxidative Maillard reactions in vivo.
LIFE SCIENCES 60 279-287. .
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PorteroOtin, M; Pamplona, R; Bellmunt, MJ; Bergua, M; Nagaraj, RH; Prat, J
Urinary pyrraline as a biochemical marker of non-oxidative Maillard reactions in vivo
LIFE SCIENCES 60 279-287. .
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PORTERO, M; Pamplona, R; Bellmunt, MJ; Nagaraj, RH; Monnier, VM; Prat, J
Ageing of proteins: Urinary excretion for pyrraline (epsilon-2-(formyl-5-hydroxymethyl-pyrrol-1-yl)-L-norleucine) formed during Maillard reaction in vivo
Journal Of Physiology-London 493P 60-60. .
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Bellmunt, MJ; PORTERO, M; Pamplona, R; Cosso, L; Odetti, P; Prat, J
Pentosidine: ageing marker for lung collagen
Journal Of Physiology-London 493P 62-62. .
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Nagaraj, RH; PorteroOtin, M; Monnier, VM
Pyrraline ether crosslinks as a basis for protein crosslinking by the advanced Maillard reaction in aging and diabetes
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 325 152-158. .
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Monnier, VM; Nagaraj, RH; PorteroOtin, M; Glomb, M; Elgawish, AH; Sell, DR; Friedlander, MA
Structure of advanced Maillard reaction products and their pathological role
NEPHROLOGY DIALYSIS TRANSPLANTATION 11 20-26. .
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Bellmunt MJ; Portero M; Pamplona R; Cosso L; Odetti P; Prat J
Evidence for the Maillard reaction in rat lung collagen and its relationship with solubility and age.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1272 53-60. .
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Bellmunt, MJ; PORTERO, M; Pamplona, R; COSSO, L; ODETTI, P; Prat, J
EVIDENCE FOR THE MaILLaRD REaCTION IN RaT LUNG COLLaGEN aND ITS RELaTIONSHIP WITH SOLUBILITY aND aGE
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1272 53-60. .
Projects
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
- "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
- Gut microbiota profile after consumption of a patented fiber formulation
- ESTRES CELULAR Y DESLOCALIZACION DE FACTORES TRANSCRIPCIONALES EN LA FISIOPATOLOGIA DE LA ELA