Directori de persones
Pascual Torres Cabestany

Pascual Torres Cabestany

Grau: Doctor/a

973- 702269
pascual.torres(ELIMINAR)@udl.cat

Grups

Publicacions

  • Torres, P; Rico-Rios, S; Ceron-Codorniu, M; Santacreu-Vilaseca, M; Seoane-Miraz, D; Jad, Y; Ayala, V; Mariño, G; Beltran, M; Miralles, MP; Andrés-Benito, P; Fernandez-Irigoyen, J; Santamaria, E; López-Otín, C; Soler, RM; Povedano, M; Ferrer, I; Pamplona, R; Wood, MJA; Varela, MA; Portero-Otin, M

    TDP-43 regulates LC3ylation in neural tissue through ATG4B cryptic splicing inhibition

    ACTA NEUROPATHOLOGICA 148 45-45. .

    [doi:10.1007/s00401-024-02780-4]

  • Ceron-Codorniu, M; Torres, P; Fernández-Bernal, A; Rico-Rios, S; Serrano, JCE; Miralles, MP; Beltran, M; Garcera, A; Soler, RM; Pamplona, R; Portero-Otín, M

    TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells

    Redox Biology 75 103301-103301. .

    [doi:10.1016/j.redox.2024.103301]

  • Gil-Sánchez A.; Gonzalo H.; Canudes M.; Nogueras L.; González-Mingot C.; Valcheva P.; Torres P.; Serrano J.C.; Peralta S.; Solana M.J.; Brieva L.

    Can Glatiramer Acetate Prevent Cognitive Impairment by Modulating Oxidative Stress in Patients with Multiple Sclerosis?

    PHARMACEUTICALS 17 -. .

    [doi:10.3390/ph17040459]

  • Sancho--Saldaña, A; Gil-Sánchez, A; González-Mingot, C; Peralta, S; Solana, MJ; Torres, P; Juanes, A; Quibus, L; Ruiz, E; Sanpedro, E; Quirant-Sánchez, B; Martínez-Cáceres, E; Tello, CR; Presas-Rodríguez, S; Rubio, SG; Baron, BP; Ramio-Torrenta, L; Sotoca, J; González-Suarez, I; Eichau, S; Prieto-Gonzalez, JM; Quilez, MRB; Sabin-Muñoz, J; Sánchez-López, AJ; Calatayud, GL; Calles, C; Sempere, AP; Garces, M; Carmona, O; Moral, E; Hervas, JV; Blanco, Y; Sola-Valls, N; Lara, NT; Forero, L; Brieva, L

    Seroprevalence of SARS-CoV-2 in Patients with Multiple Sclerosis under Disease-Modifying Therapies: A Multi-Centre Study

    Journal of Clinical Medicine 12 -. .

    [doi:10.3390/jcm12237243]

  • Torres P; Pamplona R; Portero-Otin M

    Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes.

    Neural Regeneration Research 18 1725-1726. .

    [doi:10.4103/1673-5374.363832]

  • Brewer, MK; Torres, P; Ayala, V; Portero-Otin, M; Pamplona, R; Andres-Benito, P; Ferrer, I; Guinovart, JJ; Duran, J

    Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis

    JOURNAL OF NEUROCHEMISTRY 168 744-759. .

    [doi:10.1111/jnc.15906]

  • Torres P; Sancho-Saldaña A; Gil Sánchez A; Peralta S; Solana MJ; Bakkioui S; González-Mingot C; Quibus L; Ruiz-Fernández E; San Pedro-Murillo E; Brieva L

    A prospective study of cellular immune response to booster COVID-19 vaccination in multiple sclerosis patients treated with a broad spectrum of disease-modifying therapies.

    JOURNAL OF NEUROLOGY 270 1-12. .

    [doi:10.1007/s00415-023-11575-8]

  • Muñoz-Basagoiti J; Monteiro FLL; Krumpe LRH; Armario-Najera V; Shenoy SR; Perez-Zsolt D; Westgarth HJ; Villorbina G; Bomfim LM; Raïch-Regué D; Nogueras L; Henrich CJ; Gallemí M; Moreira FRR; Torres P; Wilson J; D'arc M; Marfil S; Herlinger AL; Pradenas E; Higa LM; Portero-Otin M; Trinité B; Twyman RM; Capell T; Tanuri A; Blanco J; Izquierdo-Useros N; Rech EL; Christou P; O'Keefe BR

    Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2.

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 120 -. .

    [doi:10.1073/pnas.2214561120]

  • Torres, P; Anerillas, C; Ramirez-Nunez, O; Fernàndez A; Encinas, M; Povedano, M; Andres-Benito, P; Ferrer, I; Ayala, V; Pamplona, R; Portero-Otin, M

    The motor neuron disease mouse model hSOD1-G93A shows a non-canonical profile of senescence biomarkers.

    DISEASE MODELS & MECHANISMS 15 -. .

    [doi:10.1242/dmm.049059]

  • Sancho-Saldana, A; Gil Sánchez A; Quirant-Sanchez, B; Nogueras, L; Peralta, S; Solana, MJ; Gonzalez-Mingot, C; Gallego, Y; Quibus, L; Ramo-Tello, C; Presas-Rodriguez, S; Martinez-Caceres, E; Torres, P; Hervas, JV; Valls, J; Brieva, L

    Seroprevalence of SARS-CoV-2 in a Cohort of Patients with Multiple Sclerosis under Disease-Modifying Therapies.

    Journal of Clinical Medicine 11 -. .

    [doi:10.3390/jcm11092509]

  • Jové M; Cabré R; Mota-Martorell N; Martin-Garí M; Obis È; Ramos P; Canales I; Galo-Licona JD; Sol J; Nogueras L; Torres P; Portero-Otín M; Ayala V; Ferrer I; Pamplona R

    Age-Related Changes in Lipidome of Rat Frontal Cortex and Cerebellum Are Partially Reversed by Methionine Restriction Applied in Old Age.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 -. .

    [doi:10.3390/ijms222212517]

  • Rossi C; Fernàndez A; Torres P; Ramirez-Nuñez O; Granado-Serrano AB; Fontdevila L; Povedano M; Pamplona R; Ferrer I; Portero-Otin M

    Cell Stress Induces Mislocalization of Transcription Factors with Mitochondrial Enrichment.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 22 -. .

    [doi:10.3390/ijms22168853]

Projectes

  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Convocatòria d’Ajuts 2019 de Promoció de la Recerca en Salut – 7a Edició
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.