Directori de persones
Pascual Torres Cabestany

Pascual Torres Cabestany

Grau: Doctor/a

973- 702269
pascual.torres(ELIMINAR)@udl.cat

Publicacions

  • Torres-Querol C; Torres P; Vidal N; Portero-Otín M; Arque G; Purroy F

    Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype.

    SCIENTIFIC REPORTS 11 15752-15752. .

    [doi:10.1038/s41598-021-95344-5]

  • Ramírez-Nuñez O; Jové M; Torres P; Sol J; Fontdevila L; Romero-Guevara R; Andrés-Benito P; Ayala V; Rossi C; Boada J; Povedano M; Ferrer I; Pamplona R; Portero-Otin M

    Nuclear lipidome is altered in amyotrophic lateral sclerosis: A pilot study.

    JOURNAL OF NEUROCHEMISTRY 158 482-499. .

    [doi:10.1111/jnc.15373]

  • Sol J; Jové M; Povedano M; Sproviero W; Domínguez R; Piñol-Ripoll G; Romero-Guevara R; Hye A; Al-Chalabi A; Torres P; Andres-Benito P; Area-Gómez E; Pamplona R; Ferrer I; Ayala V; Portero-Otín M

    Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression.

    Brain Communications 3 -. .

    [doi:10.1093/braincomms/fcab143]

  • Jové M; Mota-Martorell N; Torres P; Portero-Otin M; Ferrer I; Pamplona R

    New insights into human prefrontal cortex aging with a lipidomics approach.

    EXPERT REVIEW OF PROTEOMICS 18 1-12. .

    [doi:10.1080/14789450.2021.1940142]

  • Jové M; Mota-Martorell N; Torres P; Ayala V; Portero-Otin M; Ferrer I; Pamplona R

    The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology.

    Life-Basel 11 -. .

    [doi:10.3390/life11050388]

  • Torres, P; Andres-Benito, P; Fernàndez-Bernal A; Ricart, M; Ayala, V; Pamplona, R; Ferrer, I; Portero-Otin, M

    Selected cryptic exons accumulate in hippocampal cell nuclei in Alzheimer's disease with and without associated TDP-43 proteinopathy.

    BRAIN 143 20-. .

    [doi:10.1093/brain/awaa013]

  • Torres, P; Cacabelos, D; Pairada, J; Bauer, KC; Boada, J; Fontdevila, L; Rossi, C; Povedano, M; Ferrer, I; Pamplona, R; Finlay, BB; Portero-Otin, M; Ayala, V

    Gender-Specific Beneficial Effects of Docosahexaenoic Acid Dietary Supplementation in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice.

    NEUROTHERAPEUTICS 17 269-281. .

    [doi:10.1007/s13311-019-00808-2]

  • Torres, P; Ramirez-Nunez, O; Romero-Guevara, R; Bares, G; Granado-Serrano, AB; Ayala, V; Boada, J; Fontdevila, L; Povedano, M; Sanchis, D; Pamplona, R; Ferrer, I; Portero-Otin, M

    Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue

    Autophagy 14 1398-1403. .

    [doi:10.1080/15548627.2018.1474311]

  • Cacabelos, D; Ayala, V; Granado-Serrano, AB; Jove, M; Torres, P; Boada, J; Cabre, R; Ramirez-Nunez, O; Gonzalo, H; Soler-Cantero, A; Serrano, JCE; Bellmunt, MJ; Romero, MP; Motilva, MJ; Nonaka, T; Hasegawa, M; Ferrer, I; Pamplona, R; Portero-Otin, M

    Interplay between TDP-43 and docosahexaenoic acid-related processes in amyotrophic lateral sclerosis

    NEUROBIOLOGY OF DISEASE 88 148-160. .

    [doi:10.1016/j.nbd.2016.01.007]

  • Cacabelos, D; Ramirez-Nunez, O; Granado-Serrano, AB; Torres, P; Ayala, V; Moiseeva, V; Povedano, M; Ferrer, I; Pamplona, R; Portero-Otin, M; Boada, J

    Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS

    Acta neuropathologica communications 4 3-3. .

    [doi:10.1186/s40478-015-0271-6]

Projectes

  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Convocatòria d’Ajuts 2019 de Promoció de la Recerca en Salut – 7a Edició
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.