Directori de persones
Manuel Portero Otin

Manuel Portero Otin

Grau: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Grups

Publicacions

  • Diaz-Gomez, J; Twyman, RM; Zhu, CF; Farre, G; Serrano, JCE; Portero-Otin, M; Muñoz, P.; Sandmann, G; Capell, T; Christou, P

    Biofortification of crops with nutrients: factors affecting utilization and storage

    Current Opinion In Biotechnology 44 115-123. .

    [doi:10.1016/j.copbio.2016.12.002]

  • Moreno-Navarrete, JM; Jove, M; Padro, T; Boada, J; Ortega, F; Ricart, W; Pamplona, R; Badimon, L; Portero-Otin, M; Fernandez-Real, JM

    Adipocyte Lipopolysaccharide Binding Protein (LBP) is Linked to a Specific Lipidomic Signature

    OBESITY 25 391-400. .

    [doi:10.1002/oby.21711]

  • Cabre, R; Naudi, A; Dominguez-Gonzalez, M; Ayala, V; Jove, M; Mota-Martorell, N; Piñol-Ripoll G; Gil-Villar, MP; Rue, M; Portero-Otin, M; Ferrer, I; Pamplona, R

    Sixty years old is the breakpoint of human frontal cortex aging

    FREE RADICAL BIOLOGY AND MEDICINE 103 14-22. .

    [doi:10.1016/j.freeradbiomed.2016.12.010]

  • Jove, M; Naudi, A; Gambini, J; Borras, C; Cabre, R; Portero-Otin, M; Viña J; Pamplona, R

    A Stress-Resistant Lipidomic Signature Confers Extreme Longevity to Humans

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 72 30-37. .

    [doi:10.1093/gerona/glw048]

  • Cabre, R; Jove, M; Naudi, A; Ayala, V; Piñol-Ripoll G; Gil-Villar, MP; Dominguez-Gonzalez, M; Obis È; Berdun, R; Mota-Martorell, N; Portero-Otin, M; Ferrer, I; Pamplona, R

    Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex

    Frontiers in Molecular Neuroscience 9 138-138. .

    [doi:10.3389/fnmol.2016.00138]

  • Purroy, F; Cambray, S; Mauri-Capdevila, G; Jove, M; Sanahuja, J; Farre, J; Benabdelhak, I; Molina-Seguin, J; Colàs-Campàs L; Begue, R; Gil, MI; Pamplona, R; Portero-Otin, M

    Metabolomics Predicts Neuroimaging Characteristics of Transient Ischemic Attack Patients

    EBioMedicine 14 131-138. .

    [doi:10.1016/j.ebiom.2016.11.010]

  • Moreno, JA; Diaz-Gomez, J; Nogareda, C; Angulo, E; Sandmann, G; Portero-Otin, M; Serrano, JCE; Twyman, RM; Capell, T; Zhu, CF; Christou, P

    The distribution of carotenoids in hens fed on biofortified maize is influenced by feed composition, absorption, resource allocation and storage

    SCIENTIFIC REPORTS 6 35346-35346. .

    [doi:10.1038/srep35346]

  • Jove, M; Gatius, S; Yeramian, A; Portero-Otin, M; Eritja, N; Santacana, M; Colas, E; Ruiz, M; Pamplona, R; Matias-Guiu, X

    Metabotyping human endometrioid endometrial adenocarcinoma reveals an implication of endocannabinoid metabolism

    Oncotarget 7 52364-52374. .

    [doi:10.18632/oncotarget.10564]

  • Betriu À; Farràs C; Abajo, M; Martinez-Alonso, M; Arroyo, D; Barbe, F; Buti, M; Lecube, A; Portero, M; Purroy, F; Torres, G; Valdivielso, JM; Fernandez, E

    Randomised intervention study to assess the prevalence of subclinical vascular disease and hidden kidney disease and its impact on morbidity and mortality: The ILERVAS project

    Nefrologia 36 389-396. .

    [doi:10.1016/j.nefro.2016.02.008]

  • Dominguez, M; de Oliveira, E; Odena, MA; Portero, M; Pamplona, R; Ferrer, I

    Redox proteomic profiling of neuroketal-adducted proteins in human brain: Regional vulnerability at middle age increases in the elderly

    FREE RADICAL BIOLOGY AND MEDICINE 95 1-15. .

    [doi:10.1016/j.freeradbiomed.2016.02.034]

  • Jové M; Maté I; Naudí A; Mota-Martorell N; Portero-Otín M; De la Fuente M; Pamplona R

    Human Aging Is a Metabolome-related Matter of Gender

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 71 578-585. .

    [doi:10.1093/gerona/glv074]

  • Pardo, L; Schluter, A; Valor, LM; Barco, A; Giralt, M; Golbano, A; Hidalgo, J; Jia, PL; Zhao, ZM; Jove, M; Portero-Otin, M; Ruiz, M; Gimenez-Llort, L; Masgrau, R; Pujol, A; Galea, E

    Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury

    Glia 64 853-874. .

    [doi:10.1002/glia.22969]

Projectes

  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • Gut microbiota profile after consumption of a patented fiber formulation
  • ESTRES CELULAR Y DESLOCALIZACION DE FACTORES TRANSCRIPCIONALES EN LA FISIOPATOLOGIA DE LA ELA