Directori de persones
Manuel Portero Otin

Manuel Portero Otin

Grau: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Grups

Publicacions

  • Cambray, S; Portero-Otin, M; Jove, M; Torreguitart, N; Colàs-Campàs L; Sanz, A; Benabdelhak, I; Yemisci, M; Dalkara, T; Dönmez-Demir B; Egea, J; Purroy, F

    Metabolomic Estimation of the Diagnosis and Onset Time of Permanent and Transient Cerebral Ischemia

    MOLECULAR NEUROBIOLOGY 55 6193-6200. .

    [doi:10.1007/s12035-017-0827-5]

  • Cabre, R; Naudi, A; Dominguez-Gonzalez, M; Jove, M; Ayala, V; Mota-Martorell, N; Pradas, I; Nogueras, L; Rue, M; Portero-Otin, M; Ferrer, I; Pamplona, R

    Lipid Profile in Human Frontal Cortex Is Sustained Throughout Healthy Adult Life Span to Decay at Advanced Ages

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 73 703-710. .

    [doi:10.1093/gerona/glx164]

  • Zhu, C; Farre, G; Zanga, D; Lloveras, J; Michelena, A; Ferrio, JP; Voltas, J; Slafer, G; Savin, R; Albajes, R; Eizaguirre, M; Lopez, C; Cantero-Martinez, C; Diaz-Gomez, J; Nogareda, C; Moreno, JA; Angulo, E; Estany, J; Pena, RN; Tor, M; Portero-Otin, M; Eritja, N; Arjo, G; Serrano, JCE; Matias-Guiu, X; Twyman, RM; Sandmann, G; Capell, T; Christou, P

    High-carotenoid maize: development of plant biotechnology prototypes for human and animal health and nutrition

    PHYTOCHEMISTRY REVIEWS 17 195-209. .

    [doi:10.1007/s11101-017-9506-4]

  • Lozano-Bartolome, J; Llaurado, G; Otin MP; Altuna-Coy, A; Rojo-Martinez, G; Vendrell, J; Jorba, R; Rodriguez-Gallego, E; Chacon, MR

    Altered Expression of miR-181a-5p and miR-23a-3p Is Associated With Obesity and TNF alpha-Induced Insulin Resistance

    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 103 1447-1458. .

    [doi:10.1210/jc.2017-01909]

  • Chacon, MR; Lozano-Bartolome, J; Portero-Otin, M; Rodriguez, MM; Xifra, G; Puig, J; Blasco, G; Ricart, W; Chaves, FJ; Fernandez-Real, JM

    The gut mycobiome composition is linked to carotid atherosclerosis

    BENEFICIAL MICROBES 9 185-198. .

    [doi:10.3920/BM2017.0029]

  • Berdun, R.; Font, MJ; Font-i-Furnols, M.; Moreno, J.; Rodriguez-Palmero, M.; Valent, D.; Tibau, J.; Portero-Otin, M.

    EFFECTS OF DIET SUPPLEMENTATION ON CEREBRAL POLYUNSATURATED FATTY ACID PROFILE AND PROTEIN OXIDATIVE MODIFICATION IN A PORCINE MODEL OF OBESITY

    ANNALS OF NUTRITION AND METABOLISM 73 66-66. .

  • Torres, P; Ramirez-Nunez, O; Romero-Guevara, R; Bares, G; Granado-Serrano, AB; Ayala, V; Boada, J; Fontdevila, L; Povedano, M; Sanchis, D; Pamplona, R; Ferrer, I; Portero-Otin, M

    Cryptic exon splicing function of TARDBP interacts with autophagy in nervous tissue

    Autophagy 14 1398-1403. .

    [doi:10.1080/15548627.2018.1474311]

  • Eritja, N; Jove, M; Fasmer, KE; Gatius, S; Portero-Otin, M; Trovik, J; Krakstad, C; Sol, J; Pamplona, R; Haldorsen, IS; Matias-Guiu, X

    Tumour-microenvironmental blood flow determines a metabolomic signature identifying lysophospholipids and resolvin D as biomarkers in endometrial cancer patients

    Oncotarget 8 109018-109026. .

    [doi:10.18632/oncotarget.22558]

  • Fourcade, S; Morato, L; Parameswaran, J; Ruiz, M; Ruiz-Cortes, T; Jove, M; Naudi, A; Martinez-Redondo, P; Dierssen, M; Ferrer, I; Villarroya, F; Pamplona, R; Vaquero, A; Portero-Otin, M; Pujol, A

    Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance

    AGING CELL 16 1404-1413. .

    [doi:10.1111/acel.12682]

  • Nogueras Penabad, L.; Gil Sanchez, A.; Hervas, J. V.; Gonzalez, C.; Marti, M.; Canudes, M.; Peralta, S.; Moga, M. J.; Boada, J.; Pamplona, R.; Portero, M.; Brieva, L.; Gonzalo, H.

    Mitochondrial dysfunction in peripheral blood mononuclear cells from multiple sclerosis patients

    MULTIPLE SCLEROSIS JOURNAL 23 509-509. .

  • Moreno-Navarrete, JM; Moreno, M; Ortega, F; Xifra, G; Hong, SY; Asara, JM; Serrano JCE; Jove, M; Pissios, P; Bluher, M; Ricart, W; Portero-Otin, M; Fernandez-Real, JM

    TSHB mRNA is linked to cholesterol metabolism in adipose tissue

    FASEB JOURNAL 31 4482-4491. .

    [doi:10.1096/fj.201700161R]

  • Serrano, JCE; Martin-Gari, M; Cassanye, A; Granado-Serrano, AB; Portero-Otin, M

    Characterization of the post-prandial insulinemic response and low glycaemic index of a soy beverage

    PLOS ONE 12 -. .

    [doi:10.1371/journal.pone.0182762]

Projectes

  • Natural microbicides from rice against current and emerging infectious diseases
  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.