Directori de persones
Manuel Portero Otin

Manuel Portero Otin

Grau: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Publicacions

  • Ramírez-Nuñez O; Jové M; Torres P; Sol J; Fontdevila L; Romero-Guevara R; Andrés-Benito P; Ayala V; Rossi C; Boada J; Povedano M; Ferrer I; Pamplona R; Portero-Otin M

    Nuclear lipidome is altered in amyotrophic lateral sclerosis: A pilot study.

    JOURNAL OF NEUROCHEMISTRY 158 482-499. .

    [doi:10.1111/jnc.15373]

  • Sol J; Jové M; Povedano M; Sproviero W; Domínguez R; Piñol-Ripoll G; Romero-Guevara R; Hye A; Al-Chalabi A; Torres P; Andres-Benito P; Area-Gómez E; Pamplona R; Ferrer I; Ayala V; Portero-Otín M

    Lipidomic traits of plasma and cerebrospinal fluid in amyotrophic lateral sclerosis correlate with disease progression.

    Brain Communications 3 -. .

    [doi:10.1093/braincomms/fcab143]

  • Jové M; Mota-Martorell N; Torres P; Portero-Otin M; Ferrer I; Pamplona R

    New insights into human prefrontal cortex aging with a lipidomics approach.

    EXPERT REVIEW OF PROTEOMICS 18 1-12. .

    [doi:10.1080/14789450.2021.1940142]

  • Andrés-Benito P; Gelpi E; Jové M; Mota-Martorell N; Obis È; Portero-Otin M; Povedano M; Pujol A; Pamplona R; Ferrer I

    Lipid alterations in human frontal cortex in ALS-FTLD-TDP43 proteinopathy spectrum are partly related to peroxisome impairment.

    NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 47 544-563. .

    [doi:10.1111/nan.12681]

  • Jové M; Mota-Martorell N; Torres P; Ayala V; Portero-Otin M; Ferrer I; Pamplona R

    The Causal Role of Lipoxidative Damage in Mitochondrial Bioenergetic Dysfunction Linked to Alzheimer's Disease Pathology.

    Life-Basel 11 -. .

    [doi:10.3390/life11050388]

  • Mauri-Capdevila, G; Ois, A; Jove, M; Portero, M; Sol, J; Campello, AR; Roquer, J; Vicente-Pascual, M; Justes, DV; Purroy, F

    LIPIDOMICS SIGNATURE OF STROKE RECURRENCE AFTER TRANSIENT ISCHEMIC ATTACK.

    INTERNATIONAL JOURNAL OF STROKE 15 600-600. .

  • Arnoriaga-Rodríguez M; Mayneris-Perxachs J; Burokas A; Contreras-Rodríguez O; Blasco G; Coll C; Biarnés C; Miranda-Olivos R; Latorre J; Moreno-Navarrete JM; Castells-Nobau A; Sabater M; Palomo-Buitrago ME; Puig J; Pedraza S; Gich J; Pérez-Brocal V; Ricart W; Moya A; Fernández-Real X; Ramió-Torrentà L; Pamplona R; Sol J; Jové M; Portero-Otin M; Maldonado R; Fernández-Real JM

    Obesity Impairs Short-Term and Working Memory through Gut Microbial Metabolism of Aromatic Amino Acids.

    Cell Metabolism 32 548-5607. .

    [doi:10.1016/j.cmet.2020.09.002]

  • Cunill J; Babot C; Santos L; Serrano JCE; Jové M; Martin-Garí M; Portero-Otín M

    In Vivo Anti-Inflammatory Effects and Related Mechanisms of Processed Egg Yolk, a Potential Anti-Inflammaging Dietary Supplement.

    Nutrients 12 1-11. .

    [doi:10.3390/nu12092699]

  • Jove, M; Tibau, J; Serrano, JC; Berdun, R; Rodriguez-Palmero, M; Font-I-Furnols, M; Cassanye, A; Rodriguez-Mortera, R; Sol, J; Rassendren, H; Fàbrega E; Crescenti, A; Castell, A; Sabater, M; Ortega, FJ; Martin-Gari, M; Quintanilla, R; Puigjaner, J; Moreno, JA; Prat, J; Arola, L; Fernandez-Real, JM; Pamplona, R; Portero-Otin, M

    Molecular phenomics of a high-calorie diet-induced porcine model of prepubertal obesity.

    JOURNAL OF NUTRITIONAL BIOCHEMISTRY 83 108393-108393. .

    [doi:10.1016/j.jnutbio.2020.108393]

  • Puig, J; Biarnes, C; Pedraza, S; Vilanova, JC; Pamplona, R; Fernandez-Real, JM; Brugada, R; Ramos, R; Coll-de-Tuero, G; Calvo-Perxas, L; Serena, J; Ramio-Torrenta, L; Gich, J; Gallart, L; Portero-Otin, M; Alberich-Bayarri, A; Jimenez-Pastor, A; Camacho-Ramos, E; Mayneris-Perxachs, J; Pineda, V; Font, R; Prats-Puig, A; Gacto, ML; Deco, G; Escrichs, A; Clotet, B; Paredes, R; Negredo, E; Triaire, B; Rodriguez, M; Heredia-Escamez, A; Coronado, R; de Graaf, W; Prevost, V; Mitulescu, A; Daunis-I-Estadella, P; Thio-Henestrosa, S; Miralles, F; Ribas-Ripoll, V; Puig-Domingo, M; Essig, M; Figley, CR; Figley, TD; Albensi, B; Ashraf, A; Reiber JHC; Schifitto, G; Md Nasir U; Leiva-Salinas, C; Wintermark, M; Nael, K; Vilalta-Franch, J; Barretina, J; Garre-Olmo, J

    The Aging Imageomics Study: rationale, design and baseline characteristics of the study population.

    MECHANISMS OF AGEING AND DEVELOPMENT 189 111257-111257. .

    [doi:10.1016/j.mad.2020.111257]

  • Arnoriaga-Rodriguez, M; Mayneris-Perxachs, J; Burokas, A; Perez-Brocal, V; Moya, A; Portero-Otin, M; Ricart, W; Maldonado, R; Fernandez-Real, JM

    Gut bacterial ClpB-like gene function is associated with decreased body weight and a characteristic microbiota profile.

    Microbiome 8 59-59. .

    [doi:10.1186/s40168-020-00837-6]

  • Ballester M; Quintanilla R; Ortega FJ; Serrano JCE; Cassanyé A; Rodríguez-Palmero M; Moreno-Muñoz JA; Portero-Otin M; Tibau J

    Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity.

    SCIENTIFIC REPORTS 10 5375-5375. .

    [doi:10.1038/s41598-020-62320-4]

Projectes

  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • Gut microbiota profile after consumption of a patented fiber formulation