Directori de persones
Manuel Portero Otin

Manuel Portero Otin

Grau: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Publicacions

  • Ballester M; Quintanilla R; Ortega FJ; Serrano JCE; Cassanyé A; Rodríguez-Palmero M; Moreno-Muñoz JA; Portero-Otin M; Tibau J

    Dietary intake of bioactive ingredients impacts liver and adipose tissue transcriptomes in a porcine model of prepubertal early obesity.

    SCIENTIFIC REPORTS 10 5375-5375. .

    [doi:10.1038/s41598-020-62320-4]

  • Torres, P; Andres-Benito, P; Fernàndez-Bernal A; Ricart, M; Ayala, V; Pamplona, R; Ferrer, I; Portero-Otin, M

    Selected cryptic exons accumulate in hippocampal cell nuclei in Alzheimer's disease with and without associated TDP-43 proteinopathy.

    BRAIN 143 20-. .

    [doi:10.1093/brain/awaa013]

  • Moreno, JA; Diaz-Gomez, J; Fuentes-Font, L; Angulo, E; Gosalvez, LF; Sandmann, G; Portero-Otin, M; Capell, T; Zhu, C; Christou, P; Nogareda, C

    Poultry diets containing (keto)carotenoid-enriched maize improve egg yolk color and maintain quality

    ANIMAL FEED SCIENCE AND TECHNOLOGY 260 114334-114334. .

    [doi:10.1016/j.anifeedsci.2019.114334]

  • Torres, P; Cacabelos, D; Pairada, J; Bauer, KC; Boada, J; Fontdevila, L; Rossi, C; Povedano, M; Ferrer, I; Pamplona, R; Finlay, BB; Portero-Otin, M; Ayala, V

    Gender-Specific Beneficial Effects of Docosahexaenoic Acid Dietary Supplementation in G93A-SOD1 Amyotrophic Lateral Sclerosis Mice.

    NEUROTHERAPEUTICS 17 269-281. .

    [doi:10.1007/s13311-019-00808-2]

  • Yin, XY; Willinger, CM; Keefe, J; Liu, J; Fernandez-Ortiz, A; Ibáñez B; Peñalvo J; Adourian, A; Chen, G; Corella, D; Pamplona, R; Portero-Otin, M; Jove, M; Courchesne, P; van Duijn, CM; Fuster, V; Ordovas, JM; Demirkan, A; Larson, MG; Levy, D

    Lipidomic profiling identifies signatures of metabolic risk.

    EBioMedicine 51 102520-102520. .

    [doi:10.1016/j.ebiom.2019.10.046]

  • Prieto, I; Alarcon, CR; Garcia-Gomez, R; Berdun, R; Urgel, T; Portero, M; Pamplona, R; Martinez-Ruiz, A; Ruiz-Sanz, JI; Ruiz-Larrea, MB; Jove, M; Cerdan, S; Monsalve, M

    Metabolic adaptations in spontaneously immortalized PGC-1a knock-out mouse embryonic fibroblasts increase their oncogenic potential.

    Redox Biology 29 101396-101396. .

    [doi:10.1016/j.redox.2019.101396]

  • Gubina, N; Naudi, A; Stefanatos, R; Jove, M; Scialo, F; Fernandez-Ayala, DJ; Rantapero, T; Yurkevych, I; Portero-Otin, M; Nykter, M; Lushchak, O; Navas, P; Pamplona, R; Sanz, A

    Essential Physiological Differences Characterize Short- and Long-Lived Strains of Drosophila melanogaster

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 74 1835-1843. .

    [doi:10.1093/gerona/gly143]

  • Cassanye, A; Martin-Gari, M; Portero-Otin, M; Serrano, JCE

    Adipose Tissue Mitochondrial Factors Profile after Dietary Bioactive Compound Weight Reduction Treatments in a Mice Obesity Model

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 20 -. .

    [doi:10.3390/ijms20235870]

  • Sanchez, E; Lecube, A; Betriu À; Hernandez, C; Lopez-Cano, C; Gutierrez-Carrasquilla, L; Kerkeni, M; Yeramian, A; Purroy, F; Pamplona, R; Farràs C; Fernandez, E; Barbe, F; Simo, R; ILERVAS project; Hernández M; Rius F; Polanco D; de la Torre MS; Torres G; Godoy P; Portero-Otin M; Jové M; Colàs-Compàs L; Benabdelhak I; Miquel E; Ortega M; Valdivielso JM; Bermúdez M; Martínez-Alonso M

    Subcutaneous advanced glycation end-products and lung function according to glucose abnormalities: The MR-1 ILERVAS Project

    Diabetes & metabolism 45 595-598. .

    [doi:10.1016/j.diabet.2018.04.002]

  • Casasnovas, C; Ruiz, M; Schlüter A; Naud?, A; Fourcade, S; Veciana, M; Casta?er, S; Albert?, A; Bargall?, N; Johnson, M; Raymond, GV; Fatemi, A; Moser, AB; Villarroya, F; Portero-Ot?n, M; Artuch, R; Pamplona, R; Pujol, A

    Biomarker Identification, Safety, and Efficacy of High-Dose Antioxidants for Adrenomyeloneuropathy: a Phase II Pilot Study

    NEUROTHERAPEUTICS 16 1167-1182. .

    [doi:10.1007/s13311-019-00735-2]

  • Ruiz-Plazas, X; Rodriguez-Gallego, E; Alves, M; Altuna-Coy, A; Lozano-Bartolome, J; Portero-Otin, M; Garcia-Fontgivell, JF; Martinez-Gonzalez, S; Segarra, J; Chacon, MR

    Biofluid quantification of TWEAK/Fn14 axis in combination with a selected biomarker panel improves assessment of prostate cancer aggressiveness

    Journal Of Translational Medicine 17 307-307. .

    [doi:10.1186/s12967-019-2053-6]

  • Gonzalo, H; Nogueras, L; Gil-Sanchez, A; Hervas, JV; Valcheva, P; Gonzalez-Mingot, C; Martin-Gari, M; Canudes, M; Peralta, S; Solana, MJ; Pamplona, R; Portero-Otin, M; Boada, J; Serrano JCE; Brieva, L

    Impairment of Mitochondrial Redox Status in Peripheral Lymphocytes of Multiple Sclerosis Patients

    Frontiers in Neuroscience 13 938-938. .

    [doi:10.3389/fnins.2019.00938]

Projectes

  • Natural microbicides from rice against current and emerging infectious diseases
  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.