Directori de persones
Manuel Portero Otin

Manuel Portero Otin

Grau: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Publicacions

  • Naudí A; Jové M; Cacabelos D; Ayala V; Cabre R; Caro P; Gomez J; Portero-Otín M; Barja G; Pamplona R

    Formation of S-(carboxymethyl)-cysteine in rat liver mitochondrial proteins: effects of caloric and methionine restriction

    AMINO ACIDS 44 361-371. .

    [doi:http://hdl.handle.net/10459.1/57026]

  • Jové M; Pamplona R; Prat J; Arola L; Portero-Otín M

    Atherosclerosis prevention by nutritional factors: A meta-analysis in small animal models

    NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES 23 84-93. .

    [doi:10.1016/j.numecd.2012.09.006]

  • Grimstad T; Bjørndal B; Cacabelos D; Aasprong OG; Omdal R; Svardal A; Bohov P; Pamplona R; Portero-Otin M; Berge RK; Hausken T

    A salmon peptide diet alleviates experimental colitis as compared with fish oil.

    Journal of nutritional science 2 -. .

    [doi:10.1017/jns.2012.23]

  • Bjørndal B; Grimstad T; Cacabelos D; Nylund K; Aasprong OG; Omdal R; Portero-Otin M; Pamplona R; Lied GA; Hausken T; Berge RK

    Tetradecylthioacetic Acid Attenuates Inflammation and Has Antioxidative Potential During Experimental Colitis in Rats

    DIGESTIVE DISEASES AND SCIENCES 58 97-106. .

    [doi:10.1007/s10620-012-2321-2]

  • Gonzalo, Hugo; Brieva, Luis; Tatzber, Franz; Jove, Mariona; Cacabelos, Daniel; Cassanye, Anna; Lanau-Angulo, Lucia; Boada, Jordi; Serrano, Jose C. E.; Gonzalez, Cristina; Hernandez, Lourdes; Peralta, Silvia; Pamplona, Reinald; Portero-Otin, Manuel

    Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism

    JOURNAL OF NEUROCHEMISTRY 123 622-634. .

    [doi:10.1111/j.1471-4159.2012.07934.x]

  • Vigerust, Natalya Filipchuk; Cacabelos, Daniel; Burri, Lena; Berge, Kjetil; Wergedahl, Hege; Christensen, Bjorn; Portero-Otin, Manuel; Viste, Asgaut; Pamplona, Reinald; Berge, Rolf Kristian; Bjorndal, Bodil

    Fish oil and 3-thia fatty acid have additive effects on lipid metabolism but antagonistic effects on oxidative damage when fed to rats for 50 weeks

    JOURNAL OF NUTRITIONAL BIOCHEMISTRY 23 1384-1393. .

    [doi:10.1016/j.jnutbio.2011.08.006]

  • Portero-Otin, M; Cacabelos, D; Jove, M; Ayala, V; Naudi, A; Ferrer, I; Pamplona, R

    Lipid peroxidizability as a potential trade-off of increased tissular docosahexaenoic acid concentrations in neurodegenerative processes

    FEBS Journal 279 219-220. .

  • Galea, Elena; Launay, Nathalie; Portero-Otin, Manuel; Ruiz, Montserrat; Pamplona, Reinald; Aubourg, Patrick; Ferrer, Isidre; Pujol, Aurora

    Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1822 1475-1488. .

    [doi:10.1016/j.bbadis.2012.02.005]

  • Aso, Ester; Lomoio, Selene; Lopez-Gonzalez, Irene; Joda, Laura; Carmona, Margarita; Fernandez-Yaguee, Nuria; Moreno, Jesus; Juves, Salvador; Pujol, Aurora; Pamplona, Reinald; Portero-Otin, Manuel; Martin, Virginia; Diaz, Mario; Ferrer, Isidro

    Amyloid Generation and Dysfunctional Immunoproteasome Activation with Disease Progression in Animal Model of Familial Alzheimer's Disease

    BRAIN PATHOLOGY 22 636-653. .

    [doi:10.1111/j.1750-3639.2011.00560.x]

  • Soler-Cantero, Arantza; Jove, Mariona; Cacabelos, Daniel; Boada, Jordi; Naudi, Alba; Romero, Maria-Paz; Cassanye, Anna; Serrano, Jose C. E.; Arola, Lluis; Valls, Josep; Josep Bellmunt, Maria; Prat, Joan; Pamplona, Reinald; Portero-Otin, Manuel; Motilva, Maria-Jose

    Plant-Derived Phenolics Inhibit the Accrual of Structurally Characterised Protein and Lipid Oxidative Modifications

    PLOS ONE 7 -. .

    [doi:10.1371/journal.pone.0043308]

  • Naudi, Alba; Jove, Mariona; Ayala, Victoria; Cassanye, Anna; Serrano, Jose; Gonzalo, Hugo; Boada, Jordi; Prat, Joan; Portero-Otin, Manuel; Pamplona, Reinald

    Cellular Dysfunction in Diabetes as Maladaptive Response to Mitochondrial Oxidative Stress

    EXPERIMENTAL DIABETES RESEARCH 2012 696215-696215. .

    [doi:10.1155/2012/696215]

  • Grimstad, Tore; Bjorndal, Bodil; Cacabelos, Daniel; Aasprong, Ole Gunnar; Janssen, Emiel A. M.; Omdal, Roald; Svardal, Asbjorn; Hausken, Trygve; Bohov, Pavol; Portero-Otin, Manuel; Pamplona, Reinald; Berge, Rolf K.

    Dietary supplementation of krill oil attenuates inflammation and oxidative stress in experimental ulcerative colitis in rats

    SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY 47 49-58. .

    [doi:10.3109/00365521.2011.634025]

Projectes

  • Natural microbicides from rice against current and emerging infectious diseases
  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.