Directori de persones
Manuel Portero Otin

Manuel Portero Otin

Grau: Doctor/a

973 702 408
manuel.portero(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/B-7122-2009

Publicacions

  • Das, Arindam; Pushparaj, Charumathi; Herreros, Judit; Nager, Mireia; Vilella, Ramon; Portero, Manuel; Pamplona, Reinald; Matias-Guiu, Xavier; Marti, Rosa M.; Canti, Carles

    T-type calcium channel blockers inhibit autophagy and promote apoptosis of malignant melanoma cells

    PIGMENT CELL & MELANOMA RESEARCH 26 874-885. .

    [doi:10.1111/pcmr.12155]

  • Serrano, Jose C. E.; De Lorenzo, David; Cassanye, Anna; Martin-Gari, Meritxell; Espinel, Alberto; Antonio Delgado, Marco; Pamplona, Reinald; Portero-Otin, Manuel

    Vitamin D receptor BsmI polymorphism modulates soy intake and 25-hydroxyvitamin D supplementation benefits in cardiovascular disease risk factors profile

    GENES AND NUTRITION 8 561-569. .

    [doi:10.1007/s12263-013-0356-4]

  • Naudí A; Jové M; Ayala V; Cabré R; Portero-Otin M; Ferrer I; Pamplona R

    Estudio de la vulnerabilidad neuronal selectiva en el sistema nervioso central humano.

    Revista espanola de geriatria y gerontologia 48 216-223. .

    [doi:10.1016/j.regg.2013.04.005]

  • López-Erauskin J; Galino J; Ruiz M; Cuezva JM; Fabregat I; Cacabelos D; Boada J; Martínez J; Ferrer I; Pamplona R; Villarroya F; Portero-Otín M; Fourcade S; Pujol A

    Impaired mitochondrial oxidative phosphorylation in the peroxisomal disease X-linked adrenoleukodystrophy

    HUMAN MOLECULAR GENETICS 22 3296-3305. .

    [doi:10.1093/hmg/ddt186]

  • Morató L; Galino J; Ruiz M; Calingasan NY; Starkov AA; Dumont M; Naudí A; Martínez JJ; Aubourg P; Portero-Otín M; Pamplona R; Galea E; Beal MF; Ferrer I; Fourcade S; Pujol A

    Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy

    BRAIN 136 2432-2443. .

    [doi:10.1093/brain/awt143]

  • Mauri-Capdevila, G; Jove, M; Suarez-Luis, I; Portero-Otin, M; Purroy, F

    Metabolomics in ischaemic stroke, new diagnostic and prognostic biomarkers

    REVISTA DE NEUROLOGIA 57 29-36. .

  • Jové M; Ayala V; Ramírez-Núñez O; Naudí A; Cabré R; Spickett CM; Portero-Otín M; Pamplona R

    Specific Lipidome Signatures in Central Nervous System from Methionine-Restricted Mice

    JOURNAL OF PROTEOME RESEARCH 12 2679-2689. .

    [doi:10.1021/pr400064a]

  • Arjó G; Portero M; Piñol C; Viñas J; Matias-Guiu X; Capell T; Bartholomaeus A; Parrott W; Christou P

    Plurality of opinion, scientific discourse and pseudoscience: an in depth analysis of the Seralini et al. study claiming that Roundup (TM) Ready corn or the herbicide Roundup (TM) cause cancer in rats

    TRANSGENIC RESEARCH 22 255-267. .

    [doi:10.1007/s11248-013-9692-9]

  • Jové M; Ayala V; Ramírez-Núñez O; Serrano JC; Cassanyé A; Arola L; Caimari A; Del Bas JM; Crescenti A; Pamplona R; Portero-Otín M

    Lipidomic and metabolomic analyses reveal potential plasma biomarkers of early atheromatous plaque formation in hamsters

    CARDIOVASCULAR RESEARCH 97 642-652. .

    [doi:10.1093/cvr/cvs368]

  • Serrano JC; Gonzalo-Benito H; Jové M; Fourcade S; Cassanyé A; Boada J; Delgado MA; Espinel AE; Pamplona R; Portero-Otín M

    Dietary intake of green tea polyphenols regulates insulin sensitivity with an increase in AMP-activated protein kinase content and changes in mitochondrial respiratory complexes

    MOLECULAR NUTRITION & FOOD RESEARCH 57 459-470. .

    [doi:10.1002/mnfr.201200513]

  • Keipert S; Ost M; Chadt A; Voigt A; Ayala V; Portero-Otín M; Pamplona R; Al-Hasani H; Klaus S

    Skeletal muscle uncoupling-induced longevity in mice is linked to increased substrate metabolism and induction of the endogenous antioxidant defense system

    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 304 495-506. .

    [doi:10.1152/ajpendo.00518.2012]

  • Naudí A; Jové M; Ayala V; Cabré R; Portero-Otín M; Pamplona R

    Non-Enzymatic Modification of Aminophospholipids by Carbonyl-Amine Reactions

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 14 3285-3313. .

    [doi:10.3390/ijms14023285]

Projectes

  • Natural microbicides from rice against current and emerging infectious diseases
  • Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
  • Targeting cryptic exons as biomarkers and ALS therapy
  • Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
  • The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
  • Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
  • Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
  • Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
  • Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.