Manuel Portero Otin
Grau: Doctor/a
973 702 408
manuel.portero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/B-7122-2009
Publicacions
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Jové, M.; Naudí, A.; Ramírez-Núñez, O.; Portero-Otín, M.; Selman, C.; Withers, D.J.; Pamplona, R.
Caloric restriction reveals a metabolomic and lipidomic signature in liver of male mice
AGING CELL 13 828-837. .
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Gou-Fabregas M; Ramírez-Núñez O; Cacabelos D; Bahi N; Portero M; Garcera A; Soler RM
Calpain activation and CaMKIV reduction in spinal cords from hSOD1G93A mouse model
MOLECULAR AND CELLULAR NEUROSCIENCE 61 219-225. .
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Stack C; Jainuddin S; Elipenahli C; Gerges M; Starkova N; Starkov AA; Jové M; Portero-Otin M; Launay N; Pujol A; Kaidery NA; Thomas B; Tampellini D; Beal MF; Dumont M
Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity
HUMAN MOLECULAR GENETICS 23 3716-3732. .
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Jové M; Portero-Otín M; Naudí A; Ferrer I; Pamplona R
Metabolomics of Human Brain Aging and Age-Related Neurodegenerative Diseases
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 73 640-657. .
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Granados-Principal, S.; El-azem, N.; Pamplona, R.; Ramirez-Tortosa, C.; Pulido-Moran, M.; Vera-Ramirez, L.; Quiles, J.L.; Sanchez-Rovira, P.; Naudí, A.; Portero-Otin, M.; Perez-Lopez, P.; Ramirez-Tortosa, M.
Hydroxytyrosol ameliorates oxidative stress and mitochondrial dysfunction in doxorubicin-induced cardiotoxicity in rats with breast cancer
BIOCHEMICAL PHARMACOLOGY 90 25-33. .
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Serviá, L.; Trujillano, J.; Serrano, J.C.E.; Pamplona, R.; Badia, M.; Jové, M.; Justes, M.; Domingo, J.; Portero-Otin, M.
Plasma antioxidant capacity in critical polytraumatized patients ?: methods, severity, and anatomic location
Critical Care 18 434-434. .
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Gómez, A.; Sánchez-Roman, I.; Gomez, J.; Cruces, J.; Mate, I.; Lopez-Torres, M.; Naudi, A.; Portero-Otin, M.; Pamplona, R.; De la Fuente, M.; Barja, G.
Lifelong treatment with atenolol decreases membrane fatty acid unsaturation and oxidative stress in heart and skeletal muscle mitochondria and improves immunity and behavior, without changing mice longevity
AGING CELL 13 551-560. .
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Mancuso, R.; del Valle, J.; Modol, L.; Martinez, A.; Granado-Serrano, A.B.; Ramirez-Núñez, O.; Pallás, M.; Portero-Otin, M.; Osta, R.; Navarro, X.
Resveratrol Improves Motoneuron Function and Extends Survival in SOD1(G93A) ALS Mice
NEUROTHERAPEUTICS 11 419-432. .
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Jové M; Moreno-Navarrete JM; Pamplona R; Ricart W; Portero-Otín M; Manuel Fernández-Real J
Human omental and subcutaneous adipose tissue exhibit specific lipidomic signatures
FASEB JOURNAL 28 1071-1081. .
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Fernández-Fernández, L.; Solé, M.; Bolea, I.; Valente, T.; Serrano, J.C.E.; Jové, M.; Ramirez, B.; Anglés, N.; Reguant, J.; Ramón Morelló, J.; Pamplona, R.; Portero-Otin, M.; Unzeta, M.
The Antioxidant Effect of LMN Diet, Rich in Polyphenols and Polyunsaturated Fatty Acids, in Alzheimer's Disease
The Antioxidant Effect Of Lmn Diet, Rich In Polyphenols And Polyunsaturated Fatty Acids, In Alzheimer's Disease 847-857. .
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Purroy, F; Jove, M; Mauri-Capdevila, G; Suarez, I; Cambray, S; Sanahuja, J; Benabdelhak, I; Farre, J; Portero-Otin, M
METABOLOMICS PREDICTS STROKE RECURRENCE AFTER TRANSIENT ISCHEMIC ATTACK
CEREBROVASCULAR DISEASES 37 159-160. .
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Jové M; Naudí A; Aledo JC; Cabré R; Ayala V; Portero-Otin M; Barja G; Pamplona R
Plasma long-chain free fatty acids predict mammalian longevity
SCIENTIFIC REPORTS 3 3346-3346. .
Projectes
- Natural microbicides from rice against current and emerging infectious diseases
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Targeting cryptic exons as biomarkers and ALS therapy
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Determinació de components bioactius derivats de la microbiota mitjançant micromostreig
- Estrés celulares y alteraciones en los lipidomas neuronales, gliales y extracelulares en la fisiopatología de la esclerosis lateral amiotrófica.
- "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.