Directori de persones
Olga Tarabal Mostazo

Olga Tarabal Mostazo

Grau: Doctor/a


olga.tarabal(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/C-6620-2011

Grups

Publicacions

  • Cerveró C; Montull N; Tarabal O; Piedrafita L; Esquerda JE; Calderó J

    Chronic Treatment with the AMPK Agonist AICAR Prevents Skeletal Muscle Pathology but Fails to Improve Clinical Outcome in a Mouse Model of Severe Spinal Muscular Atrophy

    NEUROTHERAPEUTICS 13 198-216. .

    [doi:10.1007/s13311-015-0399-x]

  • Gallart-Palau X; Tarabal O; Casanovas A; Sábado J; Correa FJ; Hereu M; Piedrafita L; Calderó J; Esquerda JE

    Neuregulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to alpha-motoneurons and altered during motoneuron diseases

    FASEB JOURNAL 28 3618-3632. .

    [doi:10.1096/fj.13-248583]

  • Tarabal O; Caraballo-Miralles V; Cardona-Rossinyol A; Correa FJ; Olmos G; Lladó J; Esquerda JE; Calderó J

    Mechanisms Involved in Spinal Cord Central Synapse Loss in a Mouse Model of Spinal Muscular Atrophy

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 73 519-535. .

    [doi:10.1097/NEN.0000000000000074]

  • Sabado, Javier; Casanovas, Anna; Tarabal, Olga; Hereu, Marta; Piedrafita, Ldia; Caldero, Jordi; Esquerda, Josep E.

    Accumulation of Misfolded SOD1 in Dorsal Root Ganglion Degenerating Proprioceptive Sensory Neurons of Transgenic Mice with Amyotrophic Lateral Sclerosis

    BioMed Research International 2014 -. .

    [doi:10.1155/2014/852163]

  • Caldero, J.; Brunet, N.; Tarabal, O.; Piedrafita, L.; Hereu, M.; Ayala, V.; Esquerda, J. E.

    Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord.

    NEUROSCIENCE 165 1353-1369. .

    [doi:10.1016/j.neuroscience.2009.11.034]

  • Hernández S; Casanovas A; Piedrafita L; Tarabal O; Esquerda JE

    Neurotoxic species of misfolded SOD1G93A recognized by antibodies against the P2X4 subunit of the ATP receptor accumulate in damaged neurons of transgenic animal models of amyotrophic lateral sclerosis.

    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 69 176-187. .

    [doi:10.1097/NEN.0b013e3181cd3e33]

  • Brunet, Nuria; Tarabal, Olga; Esquerda, Josep E.; Caldero, Jordi

    Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.

    Journal Of Comparative Neurology 516 277-290. .

    [doi:10.1002/cne.22118]

  • Casanovas, Anna; Hernandez, Sara; Tarabal, Olga; Rossello, Jaume; Esquerda, Josep E.

    Strong P2X4 purinergic receptor-like immunoreactivity is selectively associated with degenerating neurons in transgenic rodent models of amyotrophic lateral sclerosis.

    Journal Of Comparative Neurology 506 75-92. .

    [doi:10.1002/cne.21527]

  • Caldero, Jordi; Tarabal, Olga; Casanovas, Anna; Ciutat, Dolors; Casas, Celia; Llado, Jeronia; Esquerda, Josep E.

    Excitotoxic motoneuron disease in chick embryo evolves with autophagic neurodegeneration and deregulation of neuromuscular innervation.

    Journal Of Neuroscience Research 85 2726-2740. .

    [doi:10.1002/jnr.21174]

  • Brunet, Nuria; Tarabal, Olga; Portero-Otin, Manel; Oppenheim, Ronald W.; Esquerda, Josep E.; Caldero, Jordi

    Survival and death of mature avian motoneurons in organotypic slice culture: trophic requirements for survival and different types of degeneration.

    Journal Of Comparative Neurology 501 669-690. .

    [doi:10.1002/cne.21157]

  • Tarabal, O; CALDERO, J; Casas, C; Oppenheim, RW; ESQUERDA, JE

    Protein retention in the endoplasmic reticulum, blockade of programmed cell death and autophagy selectively occur in spinal cord motoneurons after glutamate receptor-mediated injury.

    MOLECULAR AND CELLULAR NEUROSCIENCE 29 283-298. .

    [doi:10.1016/j.mcn.2005.03.003]

  • Tarabal, O; CALDERO, J; Llado, J; Oppenheim, RW; ESQUERDA, JE

    Long-lasting aberrant tubulovesicular membrane inclusions accumulate in developing motoneurons after a sublethal excitotoxic insult: a possible model for neuronal pathology in neurodegenerative disease.

    JOURNAL OF NEUROSCIENCE 21 8072-8081. .

Projectes

  • Mecanismos subyacentes a la patología del circuito motor y la miopatía primaria en atrofia muscular espinal: identificación de dianas para terapias combinadas con nusinersen
  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • Los aferentes sinápticos de tipo C en las motoneuronas: implicaciones en la fisiopatología y terapia de la esclerosis lateral amiotrófica y de la atrofia muscular espinal (Motoneurona)
  • Caracterización fenotípica y estrategias terapéuticas en modelos murinos de atrofia muscular espinal (AME)
  • Mecanismes excitotòxics, resposta neuroinflamatòria i factors sèrics en l´esclerosi lateral amiotròfica humana i experimental