Directori de persones
Rosa Maria Soler Tatche

Rosa Maria Soler Tatche

Grau: Doctor/a

973 702 264
rosa.soler(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7361-2010

Grups

Publicacions

  • Piras, A; Schiaffino, L; Boido, M; Valsecchi, V; Guglielmotto, M; De Amicis, E; Puyal, J; Garcera, A; Tamagno, E; Soler, RM; Vercelli, A

    Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy

    CELL DEATH & DISEASE 8 3223-3223. .

    [doi:10.1038/s41419-017-0086-4]

  • Arumugam, S; Garcera, A; Soler, RM; Tabares, L

    Smn-Deficiency Increases the Intrinsic Excitability of Motoneurons

    FRONTIERS IN CELLULAR NEUROSCIENCE 11 269-269. .

    [doi:10.3389/fncel.2017.00269]

  • Periyakaruppiah, A; de la Fuente, S; Arumugam, S; Bahi, N; Garcera, A; Soler, RM

    Autophagy modulators regulate survival motor neuron protein stability in motoneurons

    EXPERIMENTAL NEUROLOGY 283 287-297. .

    [doi:10.1016/j.expneurol.2016.06.032]

  • Gou-Fabregas M; Ramírez-Núñez O; Cacabelos D; Bahi N; Portero M; Garcera A; Soler RM

    Calpain activation and CaMKIV reduction in spinal cords from hSOD1G93A mouse model

    MOLECULAR AND CELLULAR NEUROSCIENCE 61 219-225. .

    [doi:10.1016/j.mcn.2014.07.002]

  • Garcera A; Bahi N; Periyakaruppiah A; Arumugam S; Soler RM

    Survival motor neuron protein reduction deregulates autophagy in spinal cord motoneurons in vitro

    CELL DEATH & DISEASE 4 -. .

    [doi:10.1038/cddis.2013.209]

  • Caraballo-Miralles, Victor; Cardona-Rossinyol, Andrea; Garcera, Ana; Torres-Benito, Laura; Soler, Rosa M.; Tabares, Luca; Llado, Jeronia; Olmos, Gabriel

    Notch Signaling Pathway Is Activated in Motoneurons of Spinal Muscular Atrophy

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 14 11424-11437. .

    [doi:10.3390/ijms140611424]

  • Mincheva-Tasheva S; Soler RM

    NF-kappa B Signaling Pathways: Role in Nervous System Physiology and Pathology

    NEUROSCIENTIST 19 175-194. .

    [doi:10.1177/1073858412444007]

  • Caraballo-Miralles, Victor; Cardona-Rossinyol, Andrea; Garcera, Ana; Villalonga, Priam; Soler, Rosa M.; Olmos, Gabriel; Llado, Jeronia

    SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA

    MOLECULAR AND CELLULAR NEUROSCIENCE 49 282-289. .

    [doi:10.1016/j.mcn.2011.12.003]

  • Garcera, Ana; Mincheva, Stefka; Gou-Fabregas, Myriam; Caraballo-Miralles, Victor; Llado, Jeronia; Comella, Joan X.; Soler, Rosa M.

    A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons.

    NEUROBIOLOGY OF DISEASE 42 415-426. .

    [doi:10.1016/j.nbd.2011.02.003]

  • Mincheva, Stefka; Garcera, Ana; Gou-Fabregas, Myriam; Encinas, Mario; Dolcet, Xavier; Soler, Rosa M.

    The canonical nuclear factor-?B pathway regulates cell survival in a developmental model of spinal cord motoneurons.

    JOURNAL OF NEUROSCIENCE 31 6493-6503. .

    [doi:10.1523/JNEUROSCI.0206-11.2011]

  • Moubarak, Rana S.; Sole, Carme; Pascual, Marta; Gutierrez, Humberto; Llovera, Marta; Jose Perez-Garcia, M.; Gozzelino, Raffaella; Segura, Miguel F.; Iglesias-Guimarais, Victoria; Reix, Stephanie; Soler, Rosa M.; Davies, Alun M.; Soriano, Eduardo; Yuste, Victor J.; Comella, Joan X.

    The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.

    JOURNAL OF NEUROSCIENCE 30 6094-6105. .

    [doi:10.1523/JNEUROSCI.0537-10.2010]

  • Mir, M.; Asensio, V. J.; Tolosa, L.; Gou-Fabregas, M.; Soler, R. M.; Llado, J.; Olmos, G.

    Tumor necrosis factor alpha and interferon gamma cooperatively induce oxidative stress and motoneuron death in rat spinal cord embryonic explants.

    NEUROSCIENCE 162 959-971. .

    [doi:10.1016/j.neuroscience.2009.05.049]

Projectes

  • FI-SDUR
  • Identificación de nuevas dianas para el desarrollo de terapias combinadas en la Atrofia Muscular Espinal
  • Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
  • Analysis of the beneficial effects of calpain inhibitors treatment and combined therapies on Spinal Muscular Atrophy
  • Nuevas terapias para el tratamiento de la Atrofia Muscular Espinal: inhibidores de la calpaina y células madre mesenquimales modificadas
  • Desarrollo de nuevas estrategias terapéuticas para el tratamiento de la atrofia muscular espinal: regulación de la autofagia y las vías de señalización intracelular
  • Estudio degeneración de lasl motoneuronas en un model celular de atrofia muscular espinal
  • ESTUDIO SOBRE LA INTEGRACION DE LAS VIAS DE SEÑALIZACION INTRACELULAR RESPONSABLES DE LA SUPERVIVENCIA DE LAS MOTONEURONAS ESPINALES Y SU IMPLICACION EN LAS ENFERMEDADES NEURODEGENERATIVAS
  • Papel funcional del estrés oxidativo y nitrosativo en grandes sistemas biológicos.