Rosa Maria Soler Tatche
Grau: Doctor/a
973 702 264
rosa.soler(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/A-7361-2010
Publicacions
-
Gou-Fabregas, Myriam; Garcera, Ana; Mincheva, Stefka; Jose Perez-Garcia, M.; Comella, Joan X.; Soler, Rosa M.
Specific vulnerability of mouse spinal cord motoneurons to membrane depolarization.
JOURNAL OF NEUROCHEMISTRY 110 1842-1854. .
-
Perez-Garcia, M. Jose; Gou-Fabregas, Myriam; de Pablo, Yolanda; Llovera, Marta; Comella, Joan X.; Soler, Rosa M.
Neuroprotection by neurotrophic factors and membrane depolarization is regulated by calmodulin kinase IV.
Journal Of Biological Chemistry 283 4133-4144. .
-
de Pablo, Yolanda; Perez-Garcia, M. Jose; Georgieva, Maya V.; Sanchis, Daniel; Lindqvist, Niclas; Soler, Rosa M.; Comellal, Joan X.; Lloveral, Marta
Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.
JOURNAL OF NEUROCHEMISTRY 104 124-139. .
-
Fernandez-Gomez, F. J.; Pastor, M. D.; Garcia-Martinez, E. M.; de Mera, R. Melero-Fernandez; Gou-Fabregas, M.; Gomez-Lazaro, M.; Calvo, S.; Soler, R. M.; Galindo, M. F.; Jordan, J.
Pyruvate protects cerebellar granular cells from 6-hydroxydopamine-induced cytotoxicity by activating the Akt signaling pathway and increasing glutathione peroxidase expression.
NEUROBIOLOGY OF DISEASE 24 296-307. .
-
Perez-Garcia, MJ; Cena, V; de Pablo, Y; Llovera, M; Comella, JX; Soler, RM
Glial cell line-derived neurotrophic factor increases intracellular calcium concentration. Role of calcium/calmodulin in the activation of the phosphatidylinositol 3-kinase pathway.
Journal Of Biological Chemistry 279 6132-6142. .
-
Dolcet, X; Soler, RM; Gould, TW; Egea, J; Oppenheim, RW; Comella, JX
Cytokines promote motoneuron survival through the Janus kinase-dependent activation of the phosphatidylinositol 3-kinase pathway.
MOLECULAR AND CELLULAR NEUROSCIENCE 18 619-631. .
-
Egea, J; Espinet, C; Soler, RM; Dolcet, X; Yuste, VJ; Encinas, M; Iglesias, M; Rocamora, N; Comella, JX
Neuronal survival induced by neurotrophins requires calmodulin.
JOURNAL OF CELL BIOLOGY 154 585-597. .
-
Comella, J; Egea, J; Soler, RM; Dolcet, X; Espinet, C
Ca2+ and calmodulin regulate neuronal survival throughout the modulation of the intracellular signaling pathways activated by receptors for neurotrophic factors
METHOD FIND EXP CLIN 22 395-396. .
-
Egea, J; Espinet, C; Soler, RM; Peiro, S; Rocamora, N; Comella, JX
Nerve growth factor activation of the extracellular signal-regulated kinase pathway is modulated by Ca2+ and calmodulin
MOLECULAR AND CELLULAR BIOLOGY 20 1931-1946. .
-
Soler, RM; Dolcet, X; Encinas, M; Egea, J; Bayascas, JR; Comella, JX
Receptors of the glial cell line-derived neurotrophic factor family of neurotrophic factors signal cell survival through the phosphatidylinositol 3-kinase pathway in spinal cord motoneurons.
JOURNAL OF NEUROSCIENCE 19 9160-9169. .
-
Dolcet, X; Egea, J; Soler, RM; Martin-Zanca, D; Comella, JX
Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.
JOURNAL OF NEUROCHEMISTRY 73 521-531. .
-
Becker, E; Soler, RM; Yuste, VJ; Gine, E; Sanz-Rodriguez, C; Egea, J; Martin-Zanca, D; Comella, JX
Development of survival responsiveness to brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5, but not to nerve growth factor, in cultured motoneurons from chick embryo spinal cord.
JOURNAL OF NEUROSCIENCE 18 7903-7911. .
Projectes
- FI-SDUR
- Identificación de nuevas dianas para el desarrollo de terapias combinadas en la Atrofia Muscular Espinal
- Preclinical Analisis of new combinatorial treatments for spinal muscular atrophy (SMA): Effects on motorneuron survival, synaptic integrity, and skeletal muscle preservation.
- Analysis of the beneficial effects of calpain inhibitors treatment and combined therapies on Spinal Muscular Atrophy
- Nuevas terapias para el tratamiento de la Atrofia Muscular Espinal: inhibidores de la calpaina y células madre mesenquimales modificadas
- Desarrollo de nuevas estrategias terapéuticas para el tratamiento de la atrofia muscular espinal: regulación de la autofagia y las vías de señalización intracelular
- Estudio degeneración de lasl motoneuronas en un model celular de atrofia muscular espinal
- ESTUDIO SOBRE LA INTEGRACION DE LAS VIAS DE SEÑALIZACION INTRACELULAR RESPONSABLES DE LA SUPERVIVENCIA DE LAS MOTONEURONAS ESPINALES Y SU IMPLICACION EN LAS ENFERMEDADES NEURODEGENERATIVAS
- Papel funcional del estrés oxidativo y nitrosativo en grandes sistemas biológicos.