
Manuel Portero Otin
Grado: Doctor/a
973 702 408
manuel.portero(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/B-7122-2009
Grupos
Publicaciones
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Pamplona, R; Portero-Otin, M
Advanced glycation end products in urine: are some sugar-derived products better than others?
Journal Of Laboratory And Clinical Medicine 144 58-59. .
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Lambert, AJ; Portero-Otin, M; Pamplona, R; Merry, BJ
Effect of ageing and caloric restriction on specific markers of protein oxidative damage and membrane peroxidizability in rat liver mitochondria.
MECHANISMS OF AGEING AND DEVELOPMENT 125 529-538. .
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Venditti, P; De Rosa, R; Portero-Otin, M; Pamplona, R; Di Meo, S
Cold-induced hyperthyroidism produces oxidative damage in rat tissues and increases susceptibility to oxidants.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 36 1319-1331. .
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Pamplona, R; Portero-Otin, M; Sanz, A; Requena, J; Barja, G
Modification of the longevity-related degree of fatty acid unsaturation modulates oxidative damage to proteins and mitochondrial DNA in liver and brain.
Experimental Gerontology 39 725-733. .
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Portero-Otin, M; Bellmunt, MJ; Requena, JR; Pamplona, R
Protein modification by advanced Maillard adducts can be modulated by dietary polyunsaturated fatty acids.
Biochemical Society Transactions 31 1403-1405. .
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Echtay, KS; Esteves, TC; Pakay, JL; Jekabsons, MB; Lambert, AJ; Portero-Otin, M; Pamplona, R; Vidal-Puig, AJ; Wang, S; Roebuck, SJ; Brand, MD
A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.
Embo Journal 22 4103-4110. .
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Ruiz, MC; Portero-Otin, M; Pamplona, R; Requena, JR; Prat, J; Lafarga, MA; Borras, M; Bellmunt, MJ
Chemical and immunological characterization of oxidative nonenzymatic protein modifications in dialysis fluids.
Peritoneal Dialysis International 23 23-32. .
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Brand, MD; Pamplona, R; Portero-Otin, M; Requena, JR; Roebuck, SJ; Buckingham, JA; Clapham, JC; Cadenas, S
Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.
BIOCHEMICAL JOURNAL 368 597-603. .
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Pamplona, R; Portero-Otin, M; Requena, J; Gredilla, R; Barja, G
Oxidative, glycoxidative and lipoxidative damage to rat heart mitochondrial proteins is lower after 4 months of caloric restriction than in age-matched controls.
MECHANISMS OF AGEING AND DEVELOPMENT 123 1437-1446. .
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Portero-Otin, M; Pamplona, R; Bellmunt, MJ; Ruiz, MC; Prat, J; Salvayre, R; Negre-Salvayre, A
Advanced glycation end product precursors impair epidermal growth factor receptor signaling.
Diabetes 51 1535-1542. .
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Pamplona R; Barja G; PORTERO OTIN, MANUEL
Membrane fatty acid unsaturation, protection against oxidative stress, and maximum life span: a homeoviscous-longevity adaptation?
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 959 475-490. .
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Pamplona R; PORTERO OTIN, MANUEL; Bellmun MJ; Gredilla R; Barja G
Aging increases Nepsilon-(carboxymethyl)lysine and caloric restriction decreases Nepsilon-(carboxyethyl)lysine and Nepsilon-(malondialdehyde)lysine in rat heart mitochondrial proteins.
FREE RADICAL RESEARCH 36 47-54. .
Proyectos
- SEED-ALS: Synergizing Efforts to Develop and Accelerate Breakthroughs in ALS Research
- Natural microbicides from rice against current and emerging infectious diseases
- Humanised mouse models to study ATG4B cryptic exon involvement in ALS pathogenesis and its potential as disease biomarker (Hum4ALS)
- Targeting cryptic exons as biomarkers and ALS therapy
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- Comprehensive Roadmap and Preclinical Evaluation of Antisense Oligonucleotides (ASOs) Regulatory Development and Toxicological Assessment for ALS Treatment
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- Perspectivas clínicas de la biología de sistemas aplicada al análisis de placas carotídeas humanas: ILER-CAROTID
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica
- Identification of compounds for inhibition of ACE2 membrane expression
- Reposicionamiento terapéutico dirigido a inhibición de expresión de ACE2 y de proteolisis de trímero S viral
- Determinació de components bioactius derivats de la microbiota mitjançant micromostreig