Directori de persones
Daniel Sanchis Morales

Daniel Sanchis Morales

Grau: Doctor/a

973 702215/2949
daniel.sanchis(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/C-8077-2009

Grups

Publicacions

  • Chen, F; Chen, DD; Zhao, XM; Yang, S; Li, Z; Sanchis, D; Jin, L; Qiang, XZ; Wang, KY; Xu, YT; Zhang, YB; Ye, JM

    Interleukin-6 deficiency facilitates myocardial dysfunction during high fat diet-induced obesity by promoting lipotoxicity and inflammation

    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1863 3128-3141. .

    [doi:10.1016/j.bbadis.2017.08.022]

  • Yang, S; Zhao, XM; Xu, H; Chen, F; Xu, YT; Li, Z; Sanchis, D; Jin, L; Zhang, YB; Ye, JM

    AKT2 Blocks Nucleus Translocation of Apoptosis-Inducing Factor (AIF) and Endonuclease G (EndoG) While Promoting Caspase Activation during Cardiac Ischemia

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 18 -. .

    [doi:10.3390/ijms18030565]

  • Pardo, R; Blasco, N; Vila, M; Beiroa, D; Nogueiras, R; Cañas X; Simo, R; Sanchis, D; Villena, JA

    EndoG Knockout Mice Show Increased Brown Adipocyte Recruitment in White Adipose Tissue and Improved Glucose Homeostasis

    Endocrinology 157 3873-3887. .

    [doi:10.1210/en.2015-1334]

  • Inserte, J; Cardona, M; Poncelas-Nozal, M; Hernando, V; Vilardosa, U; Aluja, D; Parra, VM; Sanchis, D; Garcia-Dorado, D

    Studies on the role of apoptosis after transient myocardial ischemia: genetic deletion of the executioner caspases-3 and-7 does not limit infarct size and ventricular remodeling

    BASIC RESEARCH IN CARDIOLOGY 111 18-18. .

    [doi:10.1007/s00395-016-0537-6]

  • Cardona M; López JA; Serafín A; Rongvaux A; Inserte J; García-Dorado D; Flavell R; Llovera M; Cañas X; Vázquez J; Sanchis D

    Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart

    PLOS ONE 10 -. .

    [doi:10.1371/journal.pone.0131411]

  • Cornago M; Garcia-Alberich C; Blasco-Angulo N; Vall-Llaura N; Nager M; Herreros J; Comella JX; Sanchis D; Llovera M

    Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe

    CELL DEATH & DISEASE 5 -. .

    [doi:10.1038/cddis.2014.412]

  • Obis E; Irazusta V; Sanchís D; Ros J; Tamarit J

    Frataxin deficiency in neonatal rat ventricular myocytes targets mitochondria and lipid metabolism

    FREE RADICAL BIOLOGY AND MEDICINE 73 21-33. .

    [doi:10.1016/j.freeradbiomed.2014.04.016]

  • Moubarak RS; Planells-Ferrer L; Urresti J; Reix S; Segura MF; Carriba P; Marqués-Fernàndez F; Sole C; Llecha-Cano N; Lopez-Soriano J; Sanchis D; Yuste VJ; Comella JX

    FAIM-L Is an IAP-Binding Protein That Inhibits XIAP Ubiquitinylation and Protects from Fas-Induced Apoptosis

    JOURNAL OF NEUROSCIENCE 33 19262-19275. .

    [doi:10.1523/JNEUROSCI.2479-13.2013]

  • Giralt, Albert; Sanchis, Daniel; Cherubini, Marta; Gines, Silvia; Canas, Xavier; Comella, Joan X.; Alberch, Jordi

    Neurobehavioral characterization of Endonuclease G knockout mice reveals a new putative molecular player in the regulation of anxiety

    EXPERIMENTAL NEUROLOGY 247 122-129. .

    [doi:10.1016/j.expneurol.2013.03.028]

  • Ye J; Llorian M; Cardona M; Rongvaux A; Moubarak RS; Comella JX; Bassel-Duby R; Flavell RA; Olson EN; Smith CW; Sanchis D

    A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart

    JOURNAL OF CELL SCIENCE 126 1682-1691. .

    [doi:10.1242/jcs.121384]

  • Ye, Junmei; Cardona, Maria; Llovera, Marta; Comella, Joan X.; Sanchis, Daniel

    Translation of Myocyte Enhancer Factor-2 is induced by hypertrophic stimuli in cardiomyocytes through a Calcineurin-dependent pathway

    Journal Of Molecular And Cellular Cardiology 53 578-587. .

    [doi:10.1016/j.yjmcc.2012.07.013]

  • McDermott-Roe, Chris; Ye, Junmei; Ahmed, Rizwan; Sun, Xi-Ming; Serafin, Anna; Ware, James; Bottolo, Leonardo; Muckett, Phil; Canas, Xavier; Zhang, Jisheng; Rowe, Glenn C.; Buchan, Rachel; Lu, Han; Braithwaite, Adam; Mancini, Massimiliano; Hauton, David; Marti, Ramon; Garcia-Arumi, Elena; Hubner, Norbert; Jacob, Howard; Serikawa, Tadao; Zidek, Vaclav; Papousek, Frantisek; Kolar, Frantisek; Cardona, Maria; Ruiz-Meana, Marisol; Garcia-Dorado, David; Comella, Joan X.; Felkin, Leanne E.; Barton, Paul J. R.; Arany, Zoltan; Pravenec, Michal; Petretto, Enrico; Sanchis, Daniel; Cook, Stuart A.

    Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function.

    Nature 478 114-118. .

    [doi:10.1038/nature10490]

Projectes

  • Señalización celular en el corazón y metabolismo: supervivencia y nuevas funciones de los fibroblastos cardíacos y el papel de ENDOG en la homeostasis metabólica.
  • INVESTIGO 2022: Senyalització cel·lular i apoptosi
  • Mechanisms involved in the role of EndoG in the development and metabolism of the heart. Relationship of ENDOG and other apoptotic genes with cardiac pathophysiology
  • New molecular functions of apoptotic genes in cardiac development and stress
  • Vías de señalización para desarrollo y muerte celular en el miocardio: estudio integrativo para su comprensión e identificación de dianas terapéuticas.
  • PATHOPHYSIOLOGY AND THERAPEUTICS OF FRIENDREICH ATAXIA: MARKERS OR OXIDATIVE STRESS FROM YEAST TO CARDIOMYOCYTES
  • Identificación de nuevas funciones y miembros de la via de señalización apoptotica en el desarrollo y patologia del corazon
  • Caracterización de la función the las Deacetilasas de Histonas en la coordinación entre apoptosis y diferenciación en el corazón
  • RELEVANCIA DE LA MUERTE CELULAR POR APOPTOSIS EN PATOLOGIAS CARDIOVASCULARES QUE CURSAN CON LESION CELULAR