Juan Verdaguer Autonell
Grado: Doctor/a
973 702 210
joan.verdaguer(ELIMINAR)@udl.cat
Publicaciones
-
Amrani, A; Serra, P; Yamanouchi, J; Han, BY; Thiessen, S; Verdaguer, J; Santamaria, P
CD154-dependent priming of diabetogenic CD4(+) T cells dissociated from activation of antigen-presenting cells.
Immunity 16 719-732. .
-
Thiessen, S; Serra, P; Amrani, A; Verdaguer, J; Santamaria, P
T-cell tolerance by dendritic cells and macrophages as a mechanism for the major histocompatibility complex-linked resistance to autoimmune diabetes.
Diabetes 51 325-338. .
-
Amrani, A; Serra, P; Verdaguer, J; Yamanouchi, J; Thiessen, S; Santamaria, P
Inactivation of islet antigen-presenting cells upon engagement of Peptide/MHC class II in the absence of CD40 ligation
Diabetes 50 34-35. .
-
Amrani, A; Verdaguer, J; Serra, P; Tafuro, S; Tan, RS; Santamaria, P
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population.
Nature 406 739-742. .
-
Thiessen, S; Amrani, A; Verdaguer, J; Santamaria, P
Central tolerance as a common mechanism of diabetes protection afforded by multiple anti-diabetogenic I-a and I-E molecules
Diabetes 49 279-279. .
-
Amrani, A; Verdaguer, J; Serra, P; Tafuro, S; Tan, RS; Santamaria, P
Progression from insulitis to diabetes driven by affinity maturation of a CD8+T cell population
Diabetes 49 282-282. .
-
Amrani, A; Verdaguer, J; T'hiessen, S; Bou, S; Santamaria, P
IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes.
JOURNAL OF CLINICAL INVESTIGATION 105 459-468. .
-
Anderson, B; Park, BJ; Verdaguer, J; Amrani, A; Santamaria, P
Prevalent CD8(+) T cell response against one peptide/MHC complex in autoimmune diabetes.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 96 9311-9316. .
-
Verdaguer, J; Amrani, A; Anderson, B; Schmidt, D; Santamaria, P
Two mechanisms for the non-MHC-linked resistance to spontaneous autoimmunity.
JOURNAL OF IMMUNOLOGY 162 4614-4626. .
-
Schmidt, D; Amrani, A; Verdaguer, J; Bou, S; Santamaria, P
Autoantigen-independent deletion of diabetogenic CD4(+) thymocytes by protective MHC class II molecules
JOURNAL OF IMMUNOLOGY 162 4627-4636. .
-
Amrani, A; Verdaguer, J; Anderson, B; Utsugi, T; Bou, S; Santamaria, P
Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice.
JOURNAL OF CLINICAL INVESTIGATION 103 1201-1209. .
-
Verdaguer, J; Schmidt, D; Amrani, A; Anderson, B; Averill, N; Santamaria, P
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice.
JOURNAL OF EXPERIMENTAL MEDICINE 186 1663-1676. .
Proyectos
- Estudio del impacto generado por modificaciones en la microbiota intestinal sobre la actividad del sistema inmune en el modelo murino NOD de diabetes autoinmune.
- OncoNeoVac, un nuevo enfoque inmunoterapéutico para el tratamiento del melanoma.
- INVESTIGO 2022: Grup de Recerca en Immunologia i Metabolisme (GRIM)
- Modelación de la microbiota intestinal en las etapas iniciales del desarrollo de la diabetes autoinmune en el ratón NOD, modelo de la diabetes tipo 1 humana.
- Estudi de l'efecte adjuvant de DIF-P en una vacuna antigripal
- Linfocitos T y B anti-periferina y anti-cromogranina T and B lymphocyte durante el desarrollo de la Diabetes Mellitus Tipo 1 (APACT1D)
- Linfocitos B y T autoreactivos en la diabetes del tipo 1: Análisis funcional y desarrollo de estrategias de tratamiento (BATINT1D)
- CARACTERIZACIÓN DE LA RESPUESTA DE LINFOCITOS B AUTOREACTIVOS CONTRA UN NUEVO AUTOANTIGENO DE 90 KDA ESPECIFICO DE CELULAS BETA PANCREATICAS DURANTE EL DESARROLLO DE LA DIABETES TIPO 1
- IDENTIFICACIO DEL NOU AUTOANTIGEN ICA85 I CARACTERITZACIO DE LA RESPOSTA AUTOINMUNITARIA CONTRA AQUEST EN PACIENTS AMB DIABETIS TIPUS 1
