Publicacions
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Ceron-Codorniu, M; Torres, P; Fernández-Bernal, A; Rico-Rios, S; Serrano, JCE; Miralles, MP; Beltran, M; Garcera, A; Soler, RM; Pamplona, R; Portero-Otín, M
TDP-43 dysfunction leads to bioenergetic failure and lipid metabolic rewiring in human cells
Redox Biology 75 103301-103301. .
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Jové, M; Mota-Martorell, N; Fernàndez-Bernal, A; Portero-Otin, M; Barja, G; Pamplona, R
Phenotypic molecular features of long-lived animal species
FREE RADICAL BIOLOGY AND MEDICINE 208 728-747. .
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Bernal AF; Mota N; Pamplona R; Area-Gomez E; Portero-Otin M
Hakuna MAM-Tata: Investigating the role of mitochondrial-associated membranes in ALS.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1869 166716-166716. .
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Sol J; Obis È; Mota-Martorell N; Pradas I; Galo-Licona JD; Martin-Garí M; Fernández-Bernal A; Ortega-Bravo M; Mayneris-Perxachs J; Borrás C; Viña J; de la Fuente M; Mate I; Biarnes C; Pedraza S; Vilanova JC; Brugada R; Ramos R; Serena J; Ramió-Torrentà L; Pineda V; Daunis-I-Estadella P; Thió-Henestrosa S; Barretina J; Garre-Olmo J; Portero-Otin M; Fernández-Real JM; Puig J; Jové M; Pamplona R
Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.
AGING CELL 22 -. .
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Torres, P; Anerillas, C; Ramirez-Nunez, O; Fernàndez A; Encinas, M; Povedano, M; Andres-Benito, P; Ferrer, I; Ayala, V; Pamplona, R; Portero-Otin, M
The motor neuron disease mouse model hSOD1-G93A shows a non-canonical profile of senescence biomarkers.
DISEASE MODELS & MECHANISMS 15 -. .
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Mota-Martorell N; Andrés-Benito P; Martín-Gari M; Galo-Licona JD; Sol J; Fernández-Bernal A; Portero-Otín M; Ferrer I; Jove M; Pamplona R
Selective brain regional changes in lipid profile with human aging
Geroscience 44 763-783. .
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Torres, P; Andres-Benito, P; Fernàndez-Bernal A; Ricart, M; Ayala, V; Pamplona, R; Ferrer, I; Portero-Otin, M
Selected cryptic exons accumulate in hippocampal cell nuclei in Alzheimer's disease with and without associated TDP-43 proteinopathy.
BRAIN 143 20-. .
Projectes
- Desregulacion de TDP-43,eje clave en la ELA: Caracterización de firmas lipidómicas, transcriptómicas y autofágicas en muestras específicas de pacientes para biomarcadores y reposicionamiento
- Development of dynamic models for the personalized prevention and treatment of age-related diseases
- The role of defects in mitochondria-associated ER membranes (MAM) to Amyotrophic Lateral Sclerosis
- From GFAP mutations in astrocytes to neurodegeneration: exploring a lipid-protein oxidation pathway (ASTROMAD)
- Metabolismo lipidico intracelular, procesamiento de ARNm y estrés celular en la encrucijada de la fisiopatología de la esclerosis lateral amiotrófica