Publicacions
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Naudi, A; Cabre, R; Dominguez-Gonzalez, M; Ayala, V; Jove, M; Mota-Martorell, N; Pinol-Ripoll, G; Pilar Gil-Villar, Maria; Rue, M; Portero-Otin, M; Ferrer, I; Pamplona, R
Region-specific vulnerability to lipid peroxidation and evidence of neuronal mechanisms for polyunsaturated fatty acid biosynthesis in the healthy adult human central nervous system
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1862 485-495. .
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Cabre, R; Naudi, A; Dominguez-Gonzalez, M; Ayala, V; Jove, M; Mota-Martorell, N; Piñol-Ripoll G; Gil-Villar, MP; Rue, M; Portero-Otin, M; Ferrer, I; Pamplona, R
Sixty years old is the breakpoint of human frontal cortex aging
FREE RADICAL BIOLOGY AND MEDICINE 103 14-22. .
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Cabre, R; Jove, M; Naudi, A; Ayala, V; Piñol-Ripoll G; Gil-Villar, MP; Dominguez-Gonzalez, M; Obis È; Berdun, R; Mota-Martorell, N; Portero-Otin, M; Ferrer, I; Pamplona, R
Specific Metabolomics Adaptations Define a Differential Regional Vulnerability in the Adult Human Cerebral Cortex
Frontiers in Molecular Neuroscience 9 138-138. .
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Martinez-Cisuelo, V; Gomez, J; Garcia-Junceda, I; Naudi, A; Cabre, R; Mota-Martorell, N; Lopez-Torres, M; Gonzalez-Sanchez, M; Pamplona, R; Barja, G
Rapamycin reverses age-related increases in mitochondrial ROS production at complex I, oxidative stress, accumulation of mtDNA fragments inside nuclear DNA, and lipofuscin level, and increases autophagy, in the liver of middle-aged mice
Experimental Gerontology 83 130-138. .
Projectes
- Insight into the role of lipids in frontotemporal dementia: uncovering pathophysiological alterations and biomarker discovery opportunities.
- Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
- EFFICACY: Nuevas estrategias para incrementar efectividad de los tratamientos con ABTL0812
- "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
