Directori de persones
Reinald Pamplona Gras

Reinald Pamplona Gras

Grau: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Grups

Publicacions

  • Portero-Otin, M; Bellmunt, MJ; Ruiz, MC; Barja, G; Pamplona, R

    Correlation of fatty acid unsaturation of the major liver mitochondrial phospholipid classes in mammals to their maximum life span potential.

    Lipids 36 491-498. .

    [doi:10.1007/s11745-001-0748-y]

  • Herrero, A; Portero-Otin, M; Bellmunt, MJ; Pamplona, R; Barja, G

    Effect of the degree of fatty acid unsaturation of rat heart mitochondria on their rates of H2O2 production and lipid and protein oxidative damage.

    MECHANISMS OF AGEING AND DEVELOPMENT 122 427-443. .

    [doi:10.1016/S0047-6374(01)00214-7]

  • Pamplona, R; Portero-Otin, M; Riba, D; Requena, JR; Thorpe, SR; Lopez-Torres, M; Barja, G

    Low fatty acid unsaturation: a mechanism for lowered lipoperoxidative modification of tissue proteins in mammalian species with long life spans.

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 55 286-291. .

  • Ruiz, MC; Bellmunt, MJ; Pamplona, R; Lafarga, A; Porterootin, M

    Protein oxidative damage is selectively increased in kidney mitochondria of rats with streptozotocin-induced diabetes

    Diabetes 49 1203-1203. .

  • Portero-Otin, M; Pamplona, R; Bellmunt, MJ; Ruiz, C; Lafarga, A; Salvayre, R; Negre-Salvayre, A

    Maillard-reaction derived oxoaldehydes inhibit epidermal-growth factor receptor activity in human cultured endothelial cells

    Diabetes 49 1395-1395. .

  • Pamplona, R; Portero-Otin, M; Ruiz, C; Gredilla, R; Herrero, A; Barja, G

    Double bond content of phospholipids and lipid peroxidation negatively correlate with maximum longevity in the heart of mammals.

    MECHANISMS OF AGEING AND DEVELOPMENT 112 169-183. .

    [doi:10.1016/S0047-6374(99)00045-7]

  • Portero-Otin, M; Pamplona, R; Ruiz, MC; Cabiscol, E; Prat, J; Bellmunt, MJ

    Diabetes induces an impairment in the proteolytic activity against oxidized proteins and a heterogeneous effect in nonenzymatic protein modifications in the cytosol of rat liver and kidney.

    Diabetes 48 2215-2220. .

    [doi:10.2337/diabetes.48.11.2215]

  • Pamplona, R; Portero-Otin, M; Ruiz, C; Bellmunt, MJ; Requena, JR; Thorpe, SR; Baynes, JW; Romero, M; Lopez-Torres, M; Barja, G

    Thyroid status modulates glycoxidative and lipoxidative modification of tissue proteins.

    FREE RADICAL BIOLOGY AND MEDICINE 27 901-910. .

    [doi:10.1016/S0891-5849(99)00135-5]

  • Pamplona, R; Portero-Otin, M; Riba, D; Ledo, F; Gredilla, R; Herrero, A; Barja, G

    Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse.

    Zeitschrift Fur Gerontologie Und Geriatrie 32 883-883. .

  • Pamplona, R; Portero-Otin, M; Riba, D; Ledo, F; Gredilla, R; Herrero, A; Barja, G

    Heart fatty acid unsaturation and lipid peroxidation, and aging rate, are lower in the canary and the parakeet than in the mouse.

    Aging-Clinical And Experimental Research 11 44-49. .

  • Pamplona, R; Portero-Otin, M; Requena, JR; Thorpe, SR; Herrero, A; Barja, G

    A low degree of fatty acid unsaturation leads to lower lipid peroxidation and lipoxidation-derived protein modification in heart mitochondria of the longevous pigeon than in the short-lived rat.

    MECHANISMS OF AGEING AND DEVELOPMENT 106 283-296. .

    [doi:10.1016/S0047-6374(98)00121-3]

  • Guerrero, A; Pamplona, R; Portero-Otin, M; Barja, G; Lopez-Torres, M

    Effect of thyroid status on lipid composition and peroxidation in the mouse liver.

    FREE RADICAL BIOLOGY AND MEDICINE 26 73-80. .

    [doi:10.1016/S0891-5849(98)00173-7]

Projectes

  • Insight into the role of lipids in frontotemporal dementia: uncovering pathophysiological alterations and biomarker discovery opportunities.
  • Metabolismo de eter lípidos y envejecimiento humano
  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement