Directori de persones
Reinald Pamplona Gras

Reinald Pamplona Gras

Grau: Doctor/a

973 702 442
reinald.pamplona(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/A-7359-2010

Grups

Publicacions

  • Portero-Otin, Manuel; Pamplona, Reinald; Boada, Jordi; Jove, Mariona; Gonzalo, Hugo; Buleon, Marie; Linzc, Wolfgang; Schaefer, Stefan; Tack, Ivan; Girolami, Jean-Pierre

    Inhibition of renin angiotensin system decreases renal protein oxidative damage in diabetic rats.

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 368 528-535. .

    [doi:10.1016/j.bbrc.2008.01.101]

  • Pamplona R; Ilieva E; Ayala V; Bellmunt MJ; Cacabelos D; Dalfo E; Ferrer I; Portero-Otin M

    Maillard reaction versus other nonenzymatic modifications in neurodegenerative processes.

    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 1126 315-319. .

    [doi:10.1196/annals.1433.014]

  • Ilieva, Ekaterina V.; Ayala, VictorRia; Jove, Mariona; Dalfo, Esther; Cacabelos, Daniel; Povedano, Monica; Bellmunt, Maria Josep; Ferrer, Isidre; Pamplona, Reinald; Portero-Otin, Manuel

    Oxidative and endoplasmic reticulum stress interplay in sporadic amyotrophic lateral sclerosis.

    BRAIN 130 3111-3123. .

    [doi:10.1093/brain/awm190]

  • Naudi, Alba; Caro, Pilar; Jove, Mariona; Gomez, Jose; Boada, Jordi; Ayala, Victoria; Portero-Otin, Manuel; Barja, Gustavo; Pamplona, Reinald

    Methionine restriction decreases endogenous oxidative molecular damage and increases mitochondrial biogenesis and uncoupling protein 4 in rat brain.

    REJUVENATION RESEARCH 10 473-484. .

    [doi:10.1089/rej.2007.0538]

  • Cantero, Anne-Valerie; Portero-Otin, Manuel; Ayala, Victoria; Auge, Nathalie; Sanson, Marie; Elbaz, Meyer; Thiers, Jean-Claude; Pamplona, Reinald; Salvayre, Robert; Negre-Salvayre, Anne

    Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.

    FASEB JOURNAL 21 3096-3106. .

    [doi:10.1096/fj.06-7536com]

  • Naudi, A; Jove, M; Caro, P; Gomez, J; Lopez-Torres, M; Sanchez, I; Barja, G; Pamplona, R

    40% and 80% methionine restriction without changing other dietary components decrease oxidative stress in rat liver

    FREE RADICAL RESEARCH 41 44-44. .

  • Gomez, Jose; Caro, Pilar; Naudi, Alba; Portero-Otin, Manuel; Pamplona, Reinald; Barja, Gustavo

    Effect of 8.5% and 25% caloric restriction on mitochondrial free radical production and oxidative stress in rat liver.

    Biogerontology 8 555-566. .

    [doi:10.1007/s10522-007-9099-1]

  • Pamplona, Reinald; Barja, Gustavo

    Highly resistant macromolecular components and low rate of generation of endogenous damage: two key traits of longevity.

    AGEING RESEARCH REVIEWS 6 189-210. .

    [doi:10.1016/j.arr.2007.06.002]

  • Hulbert, A. J.; Pamplona, Reinald; Buffenstein, Rochelle; Buttemer, W. A.

    Life and death: metabolic rate, membrane composition, and life span of animals.

    PHYSIOL REV 87 1175-1213. .

    [doi:10.1152/physrev.00047.2006]

  • Ilieva, E; Naudi, A; Dalfo, E; Ayala, V; Ferrer, I; Portero-Otin, M; Pamplona, R

    Implication of oxidative and endoplasmic reticulum stress in Pick's disease

    FREE RADICAL RESEARCH 41 33-33. .

  • Ayala, Victoria; Naudi, Alba; Sanz, Alberto; Caro, Pilar; Portero-Otin, Manuel; Barja, Gustavo; Pamplona, Reinald

    Dietary protein restriction decreases oxidative protein damage, peroxidizability index, and mitochondrial complex I content in rat liver.

    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES 62 352-360. .

  • Caro, Pilar; Gomez, Jose; Sanz, Alberto; Portero-Otin, Manel; Pamplona, Reinald; Barja, Gustavo

    Effect of graded corticosterone treatment on aging-related markers of oxidative stress in rat liver mitochondria.

    Biogerontology 8 1-11. .

    [doi:10.1007/s10522-006-9026-x]

Projectes

  • Insight into the role of lipids in frontotemporal dementia: uncovering pathophysiological alterations and biomarker discovery opportunities.
  • Metabolismo de eter lípidos y envejecimiento humano
  • La vía de señalización mediada por los lípidos bioactivos diacilglicerol-ácido fosfatídico como biomarcadores para discriminar los estadios iniciales de la enfermedad de Alzheimer del envejecimiento normal
  • Identification of compounds for inhibition of ACE2 membrane expression
  • Dynamics of the neuronal, metabolomic and neuropsychological signatures underlying the adptations for motherhood during pregnancy. (babybrain)
  • Neurolipidómica del envejecimiento cerebral humano
  • "Imagenoma de l'Envelliment": Estudi observacional poblacional per definir biomarcadors d'imatge RM corporal integral i òmics que s'associen al procés d'envelliment i a factors de risc biopsicosocial en subjectes adults i que defineixen la seva trajectòria vital cap a un envelliment saludable o bé la fragilitat i discapacitat.
  • IDENTIFYING PREDICTORS OF CARDIOVASCULAR EVENTS IN CHRONIC KIDNEY DISEASE. A COHORTS SUBSTUDY WITHIN THE NEFRONA STUDY
  • Interactomas y marcadores para discriminar factores de vulnerabilidad neuronal regional en la neurodegeneración asociada al envejecimiento normal y patológico en el SNC
  • IDENTIFICACION DE BIOMARCADORES LIPIDICOS EN LIQUIDO CEFALORRAQUIDEO COMO PREDICTORES DEL DESARROLLO DE LA ENFERMEDAD DE ALZHEIMER EN PACIENTES CON DETERIORO COGNITIVO LEVE
  • ESTRES OXIDATIVO E INFLAMACION EN LA EVOLUCION DEL PROCESO DE ENVEJECIMIENTO Y PROGRESION DE LA ENFERMEDAD DE ALZHEIMER EN DIFERENTES REGIONES DEL SISTEMA NERVIOSO CENTRAL HUMANO
  • PEGASO - Personalised Guidance Services for Optimising lifesstyle in teenagers through awareness, motivation and engagement