Concepción Mora Giral
Grau: Doctor/a
973 702 958
conchi.mora(ELIMINAR)@udl.cat
ResearcherID: http://www.researcherid.com/rid/A-8280-2010
Publicacions
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Green, EA; Wong, FS; Eshima, K; Mora, C; Flavell, RA
Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.
JOURNAL OF EXPERIMENTAL MEDICINE 191 225-238. .
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Mora, C; Wong, FS; Chang, CH; Flavell, RA
Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice.
JOURNAL OF IMMUNOLOGY 162 4576-4588. .
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Palacín M; Chillarón J; Mora C
Role of the b(o,+)-like amino acid-transport system in the renal reabsorption of cystine and dibasic amino acids.
Biochemical Society Transactions 24 856-863. .
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Chillaron, J; Estevez, R; Mora, C; Wagner, CA; Suessbrich, H; Lang, F; Gelpi, JL; Testar, X; Busch, AE; Zorzano, A; Palacin, M
Obligatory amino acid exchange via systems b(o,+)-like and y(+)L-like - a tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids
Journal Of Biological Chemistry 271 17761-17770. .
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Mora, C; Chillaron, J; Calonge, MJ; Forgo, J; Testar, X; Nunes, V; Murer, H; Zorzano, A; Palacin, M
The rBAT gene is responsible for L-cystine uptake via the b0,(+)-like amino acid transport system in a "renal proximal tubular" cell line (OK cells).
Journal Of Biological Chemistry 271 10569-10576. .
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Zorzano A; Muñoz P; Camps M; Mora C; Testar X; Palacín M
Insulin-induced redistribution of GLUT4 glucose carriers in the muscle fiber. In search of GLUT4 trafficking pathways.
Diabetes 45 Suppl 1 -. .
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FURRIOLS, M; CHILLARON, J; Mora, C; CASTELLO, A; BERTRAN, J; CAMPS, M; TESTAR, X; VILARO, S; ZORZANO, A; PALACIN, M
RBaT, RELaTED TO L-CYSTINE TRaNSPORT, IS LOCaLIZED TO THE MICROVILLI OF PROXIMaL STRaIGHT TUBULES, aND ITS EXPRESSION IS REGULaTED IN KIDNEY BY DEVELOPMENT
Journal Of Biological Chemistry 268 27060-27068. .
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Furriols M; Chillarón J; Mora C; Castelló A; Bertran J; Camps M; Testar X; Vilaró S; Zorzano A; Palacín M
rBAT, related to L-cysteine transport, is localized to the microvilli of proximal straight tubules, and its expression is regulated in kidney by development.
Journal Of Biological Chemistry 268 27060-27068. .
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CARPENE, C; CHALAUX, E; LIZARBE, M; ESTRADA, A; Mora, C; PALACIN, M; ZORZANO, A; LAFONTAN, M; TESTAR, X
BETa(3)-aDRENERGIC RECEPTORS aRE RESPONSIBLE FOR THE aDRENERGIC INHIBITION OF INSULIN-STIMULaTED GLUCOSE-TRaNSPORT IN RaT aDIPOCYTES
BIOCHEMICAL JOURNAL 296 99-105. .
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GUMA, A; VINALS, F; CAMPS, M; LIZARBE, M; Mora, C; BERTRAN, J; TESTAR, X; PALACIN, M; ZORZANO, A
EFFECT OF BENZYL SUCCINaTE ON INSULIN-RECEPTOR FUNCTION aND INSULIN aCTION IN SKELETaL-MUSCLE - FURTHER EVIDENCE FOR a LaCK OF SPaRE HIGH-aFFINITY INSULIN-RECEPTORS
MOLECULAR AND CELLULAR ENDOCRINOLOGY 91 29-33. .
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GUMA, A; Mora, C; SANTALUCIA, T; VINALS, F; TESTAR, X; PALACIN, M; ZORZANO, A
SYSTEM-a TRaNSPORT aCTIVITY IS STIMULaTED IN SKELETaL-MUSCLE IN RESPONSE TO DIaBETES
FEBS LETTERS 310 51-54. .
Projectes
- INVESTIGO 2022: Grup de Recerca en Immunologia i Metabolisme (GRIM)
- DendriTHERAP: Anàlisi Transcriptòmica de cèl·lules dendrítiques novells per tal de dissenyar una teràpia per a la diabetis autoimmune
- Validación de la Ciclina D3 como regulador-clave de: la apoptosis debida a estrés del retículo endoplásmico y la función mitocondrial de la célula beta-pancreática en la diabetes (T1D).
- Identificación de nuevas vías de señalización de la ciclina D3 responsables del bienestar metabólico y viabilidad de las células beta pancreáticas en la diabetes autoinmune
- Estudi de la ciclina D3 i la CDK11 com a dianes moleculars de l'atac autoimmune vers les cél·lules beta-pancreàtiques a la diabetis de tipus 1(T1D). Determinació i caracterització de la relació causal entre la repressió de ciclina D3 i CDK11 i la mort de les cèl·lules beta-pancreàtiques.
- IMMUNOSUPRESSIO AUTOLOGA I ANTIGEN-ESPECIFICA EN LA T1DM: GENERACIO EX VIVO DE LIMFOCITS T CD4+ REGULADORS Tr1 ESPECIFICS PER A LA INSULINA AUTOLEGS MITJANÇANT CEL·LULES DENDRITIQUES (DCs)
- Estudio de la expresión diferencial de genes implicados en el ciclo celular beta-pancreático asociada a la insulitis existente en la diabetes de tipo 1 (T1D)
- Estudio de la expresión diferencial de genes implicados en el ciclo celular beta-pancraático asociada a la insulitis existente en la diabetes de Tipo 1 (T1D)