Francisco Javier Dolcet Roca
Grau: Doctor/a
ResearcherID: http://www.researcherid.com/rid/B-5665-2009
Publicacions
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Velasco, Ana; Bussaglia, Elena; Pallares, Judit; Dolcet, Xavier; Llobet, David; Encinas, Mario; Llecha, Nuria; Palacios, Jose; Prat, Jaime; Matias-Guiu, Xavier
PIK3CA gene mutations in endometrial carcinoma: correlation with PTEN and K-RAS alterations.
HUMAN PATHOLOGY 37 1465-1472. .
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Dolcet, Xavier; Llobet, David; Encinas, Mario; Pallares, Judit; Cabero, Albert; Schoenenberger, Joan Antoni; Comella, Joan X.; Matias-Guiu, Xavier
Proteasome inhibitors induce death but activate NF-kappaB on endometrial carcinoma cell lines and primary culture explants.
Journal Of Biological Chemistry 281 22118-22130. .
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Mayorga, ME; Sanchis, D; De Santos, AMP; Velasco, A; Dolcet, X; Casanova, JM; Baradad, M; Egido, R; Pallares, J; Espurz, N; Benitez, D; Mila, J; Malvehy, J; Castel, T; Comella, JX; Matias-Guiu, X; Vilella, R; Marti, RM
Antiproliferative effect of STI571 on cultured human cutaneous melanoma-derived cell lines.
MELANOMA RESEARCH 16 127-135. .
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Yuste, VJ; Sanchez-Lopez, I; Sole, C; Moubarak, RS; Bayascas, JR; Dolcet, X; Encinas, M; Susin, SA; Comella, JX
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis.
Journal Of Biological Chemistry 280 35670-35683. .
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Dolcet, X; Llobet, D; Pallares, J; Rue, M; Comella, JX; Matias-Guiu, X
FLIP is frequently expressed in endometrial carcinoma and has a role in resistance to TRAIL-induced apoptosis.
LABORATORY INVESTIGATION 85 885-894. .
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Pallares, J; Martinez-Guitarte, JL; Dolcet, X; Llobet, D; Rue, M; Palacios, J; Prat, J; Matias-Guiu, X
Survivin expression in endometrial carcinoma - a tissue microarray study with correlation with PTEN and STaT-3
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY 24 247-253. .
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Pallares J; Martínez-Guitarte JL; Dolcet X; Llobet D; Rue M; Palacios J; Prat J; Matias-Guiu X
Survivin expression in endometrial carcinoma: a tissue microarray study with correlation with PTEN and STAT-3.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY 24 247-253. .
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Dolcet, X; Llobet, D; Pallares, J; Matias-Guiu, X
NF-kB in development and progression of human cancer.
VIRCHOWS ARCHIV 446 475-482. .
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Pallares, J; Bussaglia, E; Martinez-Guitarte, JL; Dolcet, X; Llobet, D; Rue, M; Sanchez-Verde, L; Palacios, J; Prat, J; Matias-Guiu, X
Immunohistochemical analysis of PTEN in endometrial carcinoma: a tissue microarray study with a comparison of four commercial antibodies in correlation with molecular abnormalities.
Modern Pathology 18 719-727. .
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Gutierrez, H; Hale, VA; Dolcet, X; Davies, A
NF-kappaB signalling regulates the growth of neural processes in the developing PNS and CNS.
Development 132 1713-1726. .
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Pallares, J; Martinez-Guitarte, JL; Dolcet, X; Llobet, D; Rue, M; Palacios, J; Prat, J; Matias-Guiu, X
Abnormalities in the NF-kappaB family and related proteins in endometrial carcinoma.
JOURNAL OF PATHOLOGY 204 569-577. .
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Sole, C; Dolcet, X; Segura, MF; Gutierrez, H; Diaz-Meco, MT; Gozzelino, R; Sanchis, D; Bayascas, JR; Gallego, C; Moscat, J; Davies, AM; Comella, JX
The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling.
JOURNAL OF CELL BIOLOGY 167 479-492. .
Projectes
- Analysis Of Molecular Alterations And Therapeutic Targets For P53/Pten-Deficient Endometrial Cancers.
- Análisis funcional de genes supresores de tumores implicados en el cáncer de endometrio de alto riesgo mediante edición CRISPR/Cas9 in vivo
- Descifrando redes de señalización en el cáncer de endometrio: papel del microRNA-424(322)/503 neoplasias endometriales y su regulación por las vías PI3K/AKT y TGF-β/Smad (NEOSIGNAL)
- Mecanismos moleculares de progresión tumoral en modelos de neoplasias iniciadas por pérdida de PTEN (NEO-PTEN)
- DISCOVERY, VALIDATION AND IMPLEMENTATION OF BIOMARKERS FOR PRECISION ONCOLOGY
- Estudio de los efectos de la inhibición de la vía PI3K/AKT/mTOR en tumores deficientes en PTEN: mecanismos de resisitencia y nuevas estrategias terapéuticas
- MECANISMOS DE REGULACION FLIP Y LA RESPUESTA A TRAIL EN EL DESARROLLO Y PROGRESION DEL CANCER
- Caracterización de las células neoplásicas inmaduras pluripotenciales (células madre neoplásicas) en el cáncer de endometrio. Implicaciones Patogénicas, pronósticas y terapeuticas
- CARCINOMA DE ENDOMETRIO. VALORACION DELECCIONES Y AMPLIFICACIONES DE REGIONES CROMOSOMICAS MEDIANTE ARRAYS DE CGH
- Estudio de la función de la casein kinasa 2 en la tumorogénesis y desarrollo de resistencia a la apoptosis en carcinoma de endometrio
- Regulación de la apoptosis extrínseca en el cáncer de endometrio. Receptores de la familia del TNF y modulación por PTEN y NF-kB