Directori de persones
Juan Verdaguer Autonell

Juan Verdaguer Autonell

Grau: Doctor/a

973 702 210
joan.verdaguer(ELIMINAR)@udl.cat

Grups

Publicacions

  • Leeth, CM; Racine, J; Chapman, HD; Arpa, B; Carrillo, J; Carrascal, J; Wang, QM; Ratiu, J; Egia-Mendikute, L; Rosell-Mases, E; Stratmann, T; Verdaguer, J; Serreze, DV

    B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic beta-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

    Diabetes 65 1977-1987. .

    [doi:10.2337/db15-1606]

  • Carrascal, J; Carrillo, J; Arpa, B; Egia-Mendikute, L; Rosell-Mases, E; Pujol-Autonell, I; Planas, R; Mora, C; Mauricio, D; Ampudia, RM; Vives-Pi, M; Verdaguer, J

    B-cell anergy induces a Th17 shift in a novel B lymphocyte transgenic NOD mouse model, the 116C-NOD mouse

    EUROPEAN JOURNAL OF IMMUNOLOGY 46 593-608. .

    [doi:10.1002/eji.201445376]

  • Pujol-Autonell, I; Serracant-Prat, A; Cano-Sarabia, M; Ampudia, RM; Rodriguez-Fernandez, S; Sanchez, A; Izquierdo, C; Stratmann, T; Puig-Domingo, M; Maspoch, D; Verdaguer, J; Vives-Pi, M

    Use of Autoantigen-Loaded Phosphatidylserine-Liposomes to Arrest Autoimmunity in Type 1 Diabetes

    PLOS ONE 10 -. .

    [doi:10.1371/journal.pone.0127057]

  • Gómez-Touriño I; Simón-Vázquez R; Alonso-Lorenzo J; Arif S; Calviño-Sampedro C; González-Fernández A; Pena-González E; Rodríguez J; Viñuela-Roldán J; Verdaguer J; Cordero OJ; Peakman M; Varela-Calvino R

    Characterization of the autoimmune response against the nerve tissue S100 beta in patients with type 1 diabetes

    CLINICAL AND EXPERIMENTAL IMMUNOLOGY 180 207-217. .

    [doi:10.1111/cei.12572]

  • Saavedra-Ávila NA; Sengupta U; Sánchez B; Sala E; Haba L; Stratmann T; Verdaguer J; Mauricio D; Mezquita B; Ropero AB; Nadal A; Mora C

    Cyclin D3 promotes pancreatic beta-cell fitness and viability in a cell cycle-independent manner and is targeted in autoimmune diabetes

    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111 3405-3414. .

    [doi:10.1073/pnas.1323236111]

  • Garabatos N; Alvarez R; Carrillo J; Carrascal J; Izquierdo C; Chapman HD; Presa M; Mora C; Serreze DV; Verdaguer J; Stratmann T

    In Vivo Detection of Peripherin-Specific Autoreactive B Cells during Type 1 Diabetes Pathogenesis

    JOURNAL OF IMMUNOLOGY 192 3080-3090. .

    [doi:10.4049/jimmunol.1301053]

  • Mollo A; Hernandez M; Marsal JR; Esquerda A; Rius F; Blanco-Vaca F; Verdaguer J; Pozzilli P; de Leiva A; Mauricio D

    Latent autoimmune diabetes in adults is perched between type 1 and type 2: evidence from adults in one region of Spain

    DIABETES-METABOLISM RESEARCH AND REVIEWS 29 446-451. .

    [doi:10.1002/dmrr.2411]

  • Pujol-Autonell, I; Ampudia, RM; Serracant, A; Garcia, A; Aguilera, E; Puig-Domingo, M; Verdaguer, J; Vives-Pi, M

    Immunomodulatory effects of efferocytosis: a key role in the suppression of autoimmunity to beta cells

    Diabetologia 56 227-227. .

  • Pujol-Autonell, Irma; Ampudia, Rosa-Maria; Planas, Raquel; Marin-Gallen, Silvia; Carrascal, Jorge; Sanchez, Alex; Marin, Ana; Puig-Domingo, Manuel; Pujol-Borrell, Ricardo; Verdaguer, Joan; Vives-Pi, Marta

    Efferocytosis Promotes Suppressive Effects on Dendritic Cells through Prostaglandin E2 Production in the Context of Autoimmunity

    PLOS ONE 8 -. .

    [doi:10.1371/journal.pone.0063296]

  • Marin-Gallen, S.; Clemente-Casares, X.; Planas, R.; Pujol-Autonell, I.; Carrascal, J.; Carrillo, J.; Ampudia, R.; Verdaguer, J.; Pujol-Borrell, R.; Borras, F. E.; Vives-Pi, M.

    Dendritic cells pulsed with antigen-specific apoptotic bodies prevent experimental type 1 diabetes.

    CLINICAL AND EXPERIMENTAL IMMUNOLOGY 160 207-214. .

    [doi:10.1111/j.1365-2249.2009.04082.x]

  • Yamanouchi, Jun; Puertas, Maria-Carmen; Verdaguer, Joan; Lyons, Paul A.; Rainbow, Daniel B.; Chamberlain, Giselle; Hunter, Kara M.; Peterson, Laurence B.; Wicker, Linda S.; Santamaria, Pere

    Idd9.1 locus controls the suppressive activity of FoxP3+CD4+CD25+ regulatory T-cells.

    Diabetes 59 272-281. .

    [doi:10.2337/db09-0648]

  • Planas, R.; Carrillo, J.; Sanchez, A.; Ruiz de Villa, M. C.; Nunez, F.; Verdaguer, J.; James, R. F. L.; Pujol-Borrell, R.; Vives-Pi, M.

    Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes.

    CLINICAL AND EXPERIMENTAL IMMUNOLOGY 159 23-44. .

    [doi:10.1111/j.1365-2249.2009.04053.x]

Projectes

  • Estudio del impacto generado por modificaciones en la microbiota intestinal sobre la actividad del sistema inmune en el modelo murino NOD de diabetes autoinmune.
  • OncoNeoVac, un nuevo enfoque inmunoterapéutico para el tratamiento del melanoma.
  • INVESTIGO 2022: Grup de Recerca en Immunologia i Metabolisme (GRIM)
  • Modelación de la microbiota intestinal en las etapas iniciales del desarrollo de la diabetes autoinmune en el ratón NOD, modelo de la diabetes tipo 1 humana.
  • Estudi de l'efecte adjuvant de DIF-P en una vacuna antigripal
  • Linfocitos T y B anti-periferina y anti-cromogranina T and B lymphocyte durante el desarrollo de la Diabetes Mellitus Tipo 1 (APACT1D)
  • Linfocitos B y T autoreactivos en la diabetes del tipo 1: Análisis funcional y desarrollo de estrategias de tratamiento (BATINT1D)
  • CARACTERIZACIÓN DE LA RESPUESTA DE LINFOCITOS B AUTOREACTIVOS CONTRA UN NUEVO AUTOANTIGENO DE 90 KDA ESPECIFICO DE CELULAS BETA PANCREATICAS DURANTE EL DESARROLLO DE LA DIABETES TIPO 1
  • IDENTIFICACIO DEL NOU AUTOANTIGEN ICA85 I CARACTERITZACIO DE LA RESPOSTA AUTOINMUNITARIA CONTRA AQUEST EN PACIENTS AMB DIABETIS TIPUS 1