Directory
Fabien Delaspre

Fabien Delaspre

Degree: PhD


fabien.delaspre(ELIMINAR)@udl.cat

ResearcherID: http://www.researcherid.com/rid/M-3654-2015

Groups

Publications

  • Sanz-Alcázar, A; Portillo-Carrasquer, M; Delaspre, F; Pazos-Gil, M; Tamarit, J; Ros, J; Cabiscol, E

    Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3ß in the impairment of the NRF2 response

    Redox Biology 76 103339-103339. .

    [doi:10.1016/j.redox.2024.103339]

  • Alemany-Perna, B; Tamarit, J; Cabiscol, E; Delaspre, F; Miguela, A; Huertas-Pons, JM; Quiroga-Varela, A; Ruiz, MM; Dominguez, DL; Torrenta, L; Genis, D; Ros, J

    Calcitriol Treatment Is Safe and Increases Frataxin Levels in Friedreich Ataxia Patients

    MOVEMENT DISORDERS 39 1099-1108. .

    [doi:10.1002/mds.29808]

  • Sanz-Alcázar A; Britti E; Delaspre F; Medina-Carbonero M; Pazos-Gil M; Tamarit J; Ros J; Cabiscol E

    Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models.

    Cellular And Molecular Life Sciences 81 12-12. .

    [doi:10.1007/s00018-023-05064-4]

  • Alves, R; Pazos-Gil, M; Medina-Carbonero, M; Sanz-Alcazar, A; Delaspre, F; Tamarit, J

    Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues.

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 -. .

    [doi:10.3390/ijms232113151]

  • Medina-Carbonero, M; Sanz-Alcazar, A; Britti, E; Delaspre, F; Cabiscol, E; Ros, J; Tamarit, J

    Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations.

    Cellular And Molecular Life Sciences 79 74-74. .

    [doi:10.1007/s00018-021-04100-5]

  • Tamarit J; Britti E; Delaspre F; Medina-Carbonero M; Sanz-Alcázar A; Cabiscol E; Ros J

    Mitochondrial iron and calcium homeostasis in Friedreich ataxia.

    IUBMB LIFE 73 543-553. .

    [doi:10.1002/iub.2457]

  • Britti E; Delaspre F; Sanz A; Medina-Carbonero M; Llovera M; Purroy R; Mincheva-Tasheva S; Tamarit J; Ros J

    Calcitriol increases frataxin levels and restores mitochondrial function in cell models of Friedreich Ataxia.

    BIOCHEMICAL JOURNAL 478 1-20. .

    [doi:10.1042/BCJ20200331]

  • Britti, E; Delaspre, F; Tamarit, J; Ros, J

    Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na + /Ca 2+ Exchanger, NCLX, and Apoptosis.

    NEUROCHEMICAL RESEARCH 46 108-119. .

    [doi:10.1007/s11064-020-03020-3]

  • Rodríguez-Pascau L; Britti E; Calap-Quintana P; Dong YN; Vergara C; Delaspre F; Medina M; Tamarit J; Pallardó FV; Gonzalez-Cabo P; Ros J; Lynch DR; Martinell M; Pizcueta P

    PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia.

    NEUROBIOLOGY OF DISEASE 148 105162-105162. .

    [doi:10.1016/j.nbd.2020.105162]

  • Britti, Elena; Delaspre, Fabien; Tamarit, Jordi; Ros, Joaquim

    Mitochondrial calcium signalling and neurodegenerative diseases

    Neuronal Signaling 2 20180061-20180061. .

    [doi:10.1042/NS20180061]

  • Britti, E; Delaspre, F; Mincheva, S; Llovera, M; Tamarit, J; Ros, J

    Calcitriol as a supplement for Friedreich ataxia

    FEBS Open Bio 8 213-213. .

  • Britti, E; Delaspre, F; Feldman, A; Osborne, M; Greif, H; Tamarit, J; Ros, J

    Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment

    Journal Of Cellular And Molecular Medicine 22 834-848. .

    [doi:10.1111/jcmm.13365]

Projects

  • Étude comparative de souris I151F pour discerner les premières étapes de la pathogenèse del´Ataxie de Friedreich
  • Effet du Calcitriol dans un nouveau modèle murin pour l´AF de mutation ponctuelle I151F